摘要
微囊藻毒素是微囊藻等淡水藻类产生的一类具有生物活性的环状七肽物质 ,它能抑制蛋白磷酸酶 1和蛋白磷酸酶 2A的活性 ,打破细胞内蛋白磷酸化 脱磷酸化的平衡 ,引起肝损伤甚至肝坏死。而且它是强促癌剂。然而 ,其毒性及富集作用很少受到人们的重视。
Microcystins are cyclic heptapeptide hepatotoxins from certain cyanobacteria. It can inhibit hepatic protein phosphatase 1 and 2A activities, break the balance between protein phosphorylation and phosphorylysis, causing liver damage even necrocytosis. Furthermore, it is a strong tumor promoter. Yet , its hazard received little study. This paper presents a latest review of toxicity and bioaccumulation of Microcystins.
出处
《卫生研究》
CAS
CSCD
北大核心
2002年第3期214-216,F004,共4页
Journal of Hygiene Research
