摘要
目的 探讨直肠置入米索前列醇预防产后出血的效果。方法 选择 2 0 0例正常足月妊娠阴道分娩者 ,随机分为实验组和对照组。实验组 10 0例 ,在胎儿娩出后向直肠置入米索前列醇 4 0 0 μg ;对照组 10 0例 ,在胎儿前肩娩出后臀部肌肉注射缩宫素 10IU ,观察产后 2h内的出血量。结果 产后 2h内平均出血量 ,实验组 2 0 3 6 2ml,对照组 2 6 1 6 3ml,两者相比 ,差异有极显著性 (P <0 0 1) ;第三产程平均时间实验组短于对照组。结论 米索前列醇具有比缩宫素更强的子宫收缩作用 ,能减少产后出血量 ,而经直肠给药方法更为简便 。
Objective To observe the effect of misoprostol given through the rectum on postpartum bleeding in noraml parturients Lying-in women.Methods Two hundred normal parturient lying-in women were randomly into study group(n=100) and the contrast group(n=100). Parturient lying-in women in study group were given 400ug Misoprostol through the rectum. The contrasts were given 101U oxytocin immediately after the delivery of anterior shoulder of the fetus intramuscularly. The amount of bleeding within 2 hours postpartum was measured.Results The mean amount of bleeding within 2 hours for parturients lying-in women of the two groups was 203.62ml and 261.63ml respectively The differences in the amount of bleeding between the two groups were statistically significant (P<0.01). The average time that third of stage of labor in the study group was less than in the contrast group.Conclusion Misoprostol is more effective than oxytocin in controlling postpartum bleeding. Drug administration through the rectum is easy to perform and, therefore, suitable for use in rural areas. [
出处
《河南职工医学院学报》
2002年第2期115-116,共2页
Journal of Henan Medical College For Staff and Workers
