摘要
目的 探讨聚乙烯醇 (PVA)子宫动脉栓塞 (UAE)治疗子宫肌瘤的临床疗效及血流动力学的变化。方法 对21例子宫肌瘤患者采用PVA进行UAE治疗 ,并采用脉冲多普勒对术前及术后1、3、6、9、12、18个月子宫动脉平均血流速度 (Vm)、血流量 (BFV)、搏动指数 (PI)和阻力指数 (RI)进行测定。结果 Vm、BFV术后各时点较术前均有显著下降 (均P<0.01) ;PI、RI术后1、3、6个月较术前显著下降 (P<0.01) ,而术后12、18个月恢复了术前水平 (P>0.05)。术后经B超复查瘤体较术前缩小38.88%～100%。结论 使用PVA行UAE后子宫血流动力学经过少血期和恢复期变化 ,于术后12～18个月基本恢复术前水平。血流动力学的这一变化对患者的生育功能无明显影响 ,但适宜受孕时间应在术后12个月以后。
Objective To explore clinical effect and hemodynamic changes of uterine leiomyoma treated by uterine arterial embolization with polyvinyl alcohol particles(PVA-UAE). Methods Twenty one cases with uterine leiomyoma were treated by PVA-UAE .Hemodynamic changes of uterus were measured by pulsed doppler ultrasonography, including Vm,BFV,PI,and RI.Results Vm and BFV in 1, 3,6,12,18 month after operation were decreased significantly compared with those before operation(P<0.01).Decrease of PI and RI in 1,3,6 month after operation was also statistically significant compared with those before operation(P<0.01).PI and PI returned to normal levels in 12,18 month after operation(P>0.05).Tumor size decreased by 39%～100% after UAE as measured with ultrasonography. Conclusions Hemodynamic changes after PVA-UAE would take 12～18 months to return the nomal level,and have no influence upon patients' reproductive function.Variation of tumor size is related to hemodynamic changes.
出处
《浙江医学》
CAS
2002年第6期321-323,T001,共4页
Zhejiang Medical Journal
基金
浙江省医药卫生优秀青年科技人才专项资助项目(2000QN15)
