摘要
目的 :评价聚乙烯乙醇 (polyvinylalcohol,PVA)与真丝线段栓塞子宫动脉治疗子宫肌瘤的临床疗效及副反应。方法 :50例子宫肌瘤患者随机分为PVA与真丝线段栓塞两组。采用Seldinger方法经皮股动脉穿刺 ,血管造影确认子宫动脉及肌瘤所在部位后 ,超选择性子宫动脉插管并经导管注入PVA颗粒或真丝线段 ,阻断子宫肌瘤血供。治疗前后均用B超测量子宫肌瘤体积。结果 :两组患者月经量恢复正常和明显减少 ,总有效率为 97.73% ;术后 3个月和6个月肌瘤体积较治疗前缩小 4 5.81%和 51.80 % ,差异有高度显著性 (P <0 .0 1)。两组月经量和子宫肌瘤体积变化差异无显著性。两组的主要副反应是术后缺血性盆腔疼痛。术后发热症状 ,真丝线段组明显高于PVA组 (P <0 .0 5) ,无严重并发症发生。结论 :使用PVA或真丝线段超选择性子宫动脉栓塞治疗子宫肌瘤创伤小 ,近期临床疗效好 。
Objective:To evaluate the clinical effect and side effect of the treatment of hysteromyoma by uterine artery embolism with polyvinyl alcohol(PVA)and natural silk segment.Methods:50 patients of hysteromyoma was divided into two groups.Seldinger method was employed to puncture the femoral artery.After the site of uterine artery and hysteromyoma was confirmed by angiography,ultra-selective arterial cannulation was performed and PVA particles and natural silk segment was injected into uterine artery to block the blood supply of hysteromyoma. B ultrasound was used to measure the volume of the hysteromyoma before and after treatment.Results:The menstruation was recovery to normal or decreased significantly in 97.73% of all 50 patients.The volume of the hysteromyoma decreased 45.81% after 3 months and 51.80% after 6 months.The difference between the hysteromyoma volume before and after treatment was high significant (P<0.01).But there weren't significant difference in the menstruation and the hysteromyoma volume between two groups.The pelvic pain caused by ischemia was the main side effect.But feverish syndrome was more obvious in the group with natural silk segment(P<0.05).There weren't serious side effect in both groups. Conclusions:The ultra-selective uterine artery embolism with PVA or natural silk segment as a new micro-wounded therapy has a good short-term effect for hysteromyoma.Its long-term effect needs further study.
出处
《现代妇产科进展》
CSCD
2001年第2期99-101,共3页
Progress in Obstetrics and Gynecology
关键词
子宫肌瘤
动脉栓塞
聚乙烯乙醇
真丝线段
治疗
Hysteromyoma
Artery embolism
Polyvingl alcohol
Natural silk segment
