摘要
从异叶梁王茶[Nothopanax davidii(Franch)Harms]树皮中分离得到两种五环三萜皂甙,经化学和光谱(IR,~1HNMR,^(13)CNMR,~1H-~1H COSY,~1H-^(13)C COSY,NOESY,MS)分析,分别鉴定为3-O-α-(3′,4′-O-二乙酰基)-L-吡喃阿拉伯糖-β-羟齐墩果-12-烯-28,29-双羧酸-28-O-[α-L-吡喃鼠李糖(1→6)-β-D-吡喃葡萄糖(1→4)-β-D-吡喃葡萄糖]酯甙(Ⅱ)和3-O-α-(3′-O-乙酰基)-L-吡喃阿拉伯糖-3β-羟齐墩果-12-烯-28,29-双羧酸甙(Ⅱ),前者命名为异叶梁王茶甙Ⅰ,后者命名为异叶梁王茶甙Ⅱ。这两个皂甙均系新化合物。
Two new oleanane type triterpene glycosides ,named yiyeliangwanoside Ⅰ and yiyeliangwanoside Ⅱ, were isolated from Nothopanax davidii (Franch) Harms (Araliaceae). Their chemical structures were elucidated by means of chemical and spectrometric analysis.Yiyeliangwanoside I: C_(57)H_(88)O_(25), a white powder, mp 203～205℃ (dec.), [x]_D^(20)- 3.47 (c 0.1, CH_3OH). Its structure was determined as 3 -O-α-(3′, 4′-O-dioic- acetyl )- L - arabinopyranosyl - 3β - hydroxyolean - 12 -ene - 28,29 - dioic acid - 28- O - [α- L - rhamnopyranosyl - ( 1→6)-β- D - glycopyranosyl - (1→4)-β - D -glycopyranosyl] ester.Yiyeliangwanoside Ⅱ : C_(37)H_(56)O_(10), a white powder, mp 240 - 244℃ (dec.),[α]_D^(20)+ 36.5 (c 0.1 , CH_3OH ). Its structure was determined as 3 - O -α - (3' - O - acetyl )- L - arabinopyranosyl -3β - hydroxyolean - 12 - ene - 28,29 - dioic acid.
出处
《药学学报》
CAS
CSCD
北大核心
1991年第4期261-266,共6页
Acta Pharmaceutica Sinica
关键词
异叶梁王茶
化学成分
Nothopanax davidii
Triterpene saponin
Yiyeliangwanoside I
Yiyeliangwanoside Ⅱ
2D-NMR
