摘要
目的 研究高血压病 (EH)和 2型糖尿病 (DM)患者餐后状态血压和心率的变化特点。 方法 187例患者 ,分 3组 :高血压病组 (EH,71例 ) ,2型糖尿病组 (DM,49例 )和 2型糖尿病伴高血压组 (DM+EH,6 7例 )。观察各组 2 4h动态血压和心率 ,进标准定量饮食 ,分析进餐前后收缩压(SBP)、舒张压 (DBP)和心率的变化。 结果 EH组和 DM+EH组 2 4h平均收缩压 (2 4h ABPS)和2 4h平均舒张压 (2 4h ABPD)较 DM组明显增高 (P<0 .0 1) ,而 DM组和 DM+EH组 2 4h平均心率较 EH组快 (P<0 .0 1) ;EH组在餐后 30 m in至 6 0 min的 SBP、DBP和心率较餐前对应时间点升高(P<0 .0 1) ,餐后 90 m in SBP、DBP和心率恢复至餐前水平。 DM组和 DM+EH组在餐后 30 m in至90 min SBP、DBP和心率下降 (P<0 .0 1) ,餐后 12 0 min SBP、DBP和心率恢复至餐前水平。 结论 高血压病和 2型糖尿病患者餐后状态血压和心率的变化有不同的特点 ,表现为高血压病患者餐后血压升高和心率增快 ,而 2型糖尿病或伴高血压病的 2型糖尿病患者餐后血压和心率下降 ,且其血压和心率恢复至餐前水平较单纯高血压病患者慢。
Objective To study the change in postprandial blood pressure and heart rate in hypertensive and type 2 diabetic patients. Methods Subjects were assigned to three groups: the essential hypertension (EH, n= 71); the type 2 diabetes mellitus (DM, n= 49) and the hypertension with DM (DM+EH, n= 67). We evaluated changes in blood pressure and heart rate after a meal by 24 hour blood pressure monitoring in 187 hospitalized patients who received a diet containing standarded nutritional in lunch. Results From 30 min to 60 min after the test meal, the postprandial blood pressure and heart rate increased in the EH subgroup ( P <0.01),and recovered after 90 min,however,the postprandial blood pressure and heart rate decreased significandly in the DM subgroup and DM+EH subgroup from the 30 min to 90 min ( P <0.01),and recovered after 120 min .Heart rate of the DM and DM+EH group was higher than that of EH group before a diet ( P <0.01). Conclusion There were significant differences in postprandial blood pressure and heart rate between essential hypertensive patients and DM patients. The postprandial blood pressure and heart rate increased in the EH, but decreased in the DM and DM+EH.
出处
《中国糖尿病杂志》
CAS
CSCD
2002年第3期139-141,共3页
Chinese Journal of Diabetes
基金
国家自然科学基金资助项目 (基金编号 3972 5 0 13)
