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NF-κB及其在肿瘤中的生物学行为特征 被引量：4

NF-κB and it's characters of biological behaviors in tumor
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摘要 NF κB是一类普遍存在的转录因子 ,参与着 15 0余种基因的转录调控 ,主要涉及免疫炎症反应、细胞增殖与凋亡等生物学过程。NF κB可被许多刺激因素激活。近年来 ,围绕着NF κB在肿瘤中的生物学行为特征这一问题进行了大量研究 ,本文综述NF κB在肿瘤的发生、浸润、转移和耐药中的作用等方面的进展。
作者 牛永东
机构地区 汕头大学医学院生物化学与分子生物学教研室
出处 《国外医学（肿瘤学分册）》 CAS 2002年第3期168-171,共4页 Foreign Medical Sciences (Cancer Section)
基金 国家自然科学基金项目 (3 990 0 0 69和 3 0 170 42 8) 广东省自然科学基金资助项目 (990 799和 0 10 43 1) 广东省高校自然科学科研项目 (2 0 0 0 3 3 )
关键词 NF-ΚB 肿瘤 生物学行为 诊断 治疗 信号传导通路
分类号 R73-36 [医药卫生—肿瘤]
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参考文献20

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同被引文献37

  • 1Scaife CL, Kuang J,Wills JC, et al. Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis[ J]. Cancer Res ,2002,62 ( 23 ) :6870-6878.
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国外医学（肿瘤学分册）
2002年 第3期

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