摘要
目的 :探讨肿瘤病人的心理社会因素与免疫功能的相关性。方法 :用病例对照和多因素统计分析方法 ,对 37例肿瘤病人和 37例非肿瘤病人进行了心理社会因素调查并检测其免疫功能 ,分析其间的相互关系。结果 :肿瘤病人与非肿瘤病人相比免疫功能明显减退 ,主要表现为IgM、CD16+ 水平的减少 (P <0 0 1 ) ,肿瘤病人的IgM、CD3 + 与负性生活事件、社会支持、抑郁情绪等因素相关。结论 :肿瘤病人的免疫功能低下主要表现在IgM ,CD16+ 水平的减少。负性生活事件、社会支持。
Objective: To study the relationship between immune function and psychosocial factors of patients with malignant tumors Method:37 inpatients with malignant tumors were collected They had no chemotherapy or radiotherapy in the past month and without history of immune disease or medication influencing immune system 37 inpatients of internal department without tumor were collected as control All subjects completed EPQ, SCL-90, SAS, SDS, LES, SSRS and DSQ Researchers assessed their mood with HAMA and HAMD, and their immune function by measuring serum IgG, IgA, IgM, C 3, C 4, CH50 and sub-groups of lymphocyte Results:Study group had lower IgM and less CD 16 + than control The level of IgM was associated with course of disease, educational level, gender, personality, defense style, negative life events and social support The level of CD 3 + was associated with depression in addition to other factors mentioned above Conclusion: Patients with malignant tumors have immune dysfunction, which associated with psychosocial factors such as negative life events, social support and depression
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2002年第6期386-389,共4页
Chinese Mental Health Journal
