摘要
目的探讨汽车尾气对红细胞免疫粘附功能的影响。方法使昆明种雄性小鼠吸入汽油车尾气每天20min ,连续20d。观察小鼠脾脏的脏体系数和外周血红细胞计数 ,以补体致敏酵母血凝法检测红细胞免疫粘附功能。结果暴露于汽车尾气的小鼠脾脏系数[(4 84±0 53)mg/g]和红细胞计数[(5 83×1012±0 25×1012)个/L]均显著低于对照组[(5 55±0 68)mg/g,(7 71×1012±0 29×1012)个/L] ;当血凝滴度为1∶8时 ,暴露组血凝阳性率(12 5%)显著低于对照组(82 5%) ,χ2=39 2,P<0 05。结论汽车尾气使小鼠红细胞免疫粘附功能受到抑制。
Objective To explore the effects of automobil exhaust on immune adherence function of erythrocytes in mice Methods The male Kunming mice were exposed to gasoline fueled engine exhausts 20 minutes per day continouusly for 20 days After the whole exposure,the ratio of spleen to body weight and total count of erythrocytes in peripheral blood of mice were observed The immune adherence function of erythrocytes was determined by complement sensitized yeast cell hemagglutination test in mice Results The ratio of spleen to body weight [(4.84±0.53)mg/g] and total count of erythrocytes [(5 83×10 12±0 25×10 12)/L] of mice exposed to automobil exhausts were significantly lower than those of control group [(5 55±0 68)mg/kg,(7 71×10 12±0 29×10 12)/L] respectively The positive rate of blood coagulation of exposure group (12 5%) was significantly lower than that of control group (82 5%) at blood coagulation titer of 1∶8,χ 2=39 2,P<0 05 Conclusion The inhalation of automobil exhausts might result in the inhibition of immune adherence function of mice erythrocytes
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2002年第2期109-110,共2页
Journal of Environment and Health
关键词
汽车废气
红细胞
免疫粘附反应
血凝试验
Automobil exhausts
Erythrocytes
Immune adherence reaction
Hemagglutination test
