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外照射加^(89)Sr内照射治疗多发性骨转移瘤疗效分析 被引量:2

Analysis on the effect of radiotherapy combined with ^(89)Sr for multiple bone metastases
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摘要 目的 探讨外照射加89Sr内照射治疗多发性骨转移瘤的效果。方法  42例多发性骨转移瘤患者进行放射治疗。直线加速器 6MV X线外照射 ,2~ 3Gy/次 ,DT30~ 5 4Gy。其中 18例在外照射结束 1~ 2周后行89Sr内照射 ,剂量为2 .2 2MBq/kg。结果 外照射加89Sr内照射组 (综合组 )疼痛缓解率为 94.4% ,单纯外照射组 (单放组 )缓解率为 83.3% (X2=1.2 1,P >0 .2 5 ) ,疼痛平均缓解时间综合组为 6个月 ,单放组 4.5个月。结论 外照射加89Sr内照射治疗多发性骨转移瘤为较有效的治疗方法。 Objective To study the effect of radiotherapy combined with 89 Sr on multiple bone metastases.Methods Forty-tow cases of multiple bone metastases were received radiotherapy by means of 6-MV photons from a linear accelerator with a total dose of 30~54 Gy(2~3 Gy per fraction).After 1~2 weeks,18 cases were further treated by 89 Sr at the dosage of 2.22MBq/Kg.Results The overall effective rate of radiotherapy combined with 89 Sr group (combined group) and radiotherapy alone group were 94.4% and 83.3%,respectively (X 2=1.21,P>0.25).The median relief time of combined group and radiotherapy alone group were 6 and 4.5 months respectively.Conclusion The effects would be better if radiotherapy combined with 89 Sr in the management of multiple bone metastases.
作者 马剑波 季斌
出处 《中国肿瘤临床与康复》 2002年第3期103-104,共2页 Chinese Journal of Clinical Oncology and Rehabilitation
关键词 外照射 内照射 骨转移瘤 疗效分析 放射治疗 锶89 bone metastasis radiotherapy 89 Sr
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