摘要
目的 探讨宫颈分泌物中胰岛素样生长因子结合蛋白 - 1 (IGFBP - 1 )的高磷酸化异构体在预测宫颈成熟度中的价值。方法 应用免疫层析法检测Bishop评分不同的 1 0 2例足月妊娠的孕妇宫颈分泌物中IGFBP - 1的高磷酸化异构体。 结果 IGFBP - 1阳性率随宫颈成熟的程度升高而升高 ,宫颈成熟组IGFBP - 1阳性率与未成熟组比较 ,差异有显著性 (P <0 .0 5)。结论 IGFBP - 1的高磷酸化异构体与宫颈的成熟度有关 ,对早产的预测与计划分娩的实施有一定的指导作用。
Objective To study the value of the phosphorylated isoforms of insulin-like growth factor binding protein-1 (IGFBP-1) in cervical secretion in the prediction of cervical ripeness. Methods 102 cases of term pregnant women, who got different Bishop scores, received test by using immunochromatography about their phosphorylated isoforms of IGFBP-1 in their cervical secretion. Results The positive rate of IGFBP-1 rises with the ripeness of cervix, and the difference of the positive rate of IGFBP-1between the favorable cervix group and the unfavorable group was significant (P<0.05). Conclusion Phosphorulated isoforms of IGFBP-1 reflects the cervical ripeness and may be valuable in the prediction of preterm labor and in the instruction of the designed delivery.
出处
《中国煤炭工业医学杂志》
2002年第5期424-425,共2页
Chinese Journal of Coal Industry Medicine
基金
广东省科委科研基金(1 998- 0 4 )资助课题
