摘要
目的 :探讨肥胖对高血压左室肥厚 (LVH)的影响及两者之间的关系。方法 :应用超声心动图检测4 6例高血压肥胖患者左室心肌重量 (LVM)及左室心肌重量指数 (LVMI) ,并与 4 8例高血压非肥胖患者及 19例正常对照者进行比较 ,了解高血压伴肥胖者LVH的发生率和相对危险度。结果 :高血压肥胖患者的LVM明显高于高血压非肥胖者和正常对照者 [(2 30 .18± 6 3.99) g∶(2 0 0 .4 8± 5 9.0 4 ) g和 (16 1.5 8± 38.5 4 ) g ,P <0 .0 5 ,P<0 .0 1];高血压肥胖者的LVMI也较正常对照组明显增加 [(12 7.81± 34.4 4 )∶(98.0 1± 2 1.6 5 ) ,P <0 .0 5 ],但与高血压非肥胖组 (118.86± 33.2 3)相比无统计学差异 (P >0 .0 5 ) ;高血压肥胖患者LVH检出率也较高血压非肥胖者明显增高 (6 0 .9%∶39.6 % ,P <0 .0 5 ) ,前者发生LVH的相对危险度是后者的 2 .37倍。结论 :肥胖对高血压LVH有促进作用。
Objective:To assess the effects of obesity on left ventricular hypertrophy in patients with hypertension. Method:Using echocardiography technique, we measured left ventricular mass (LVM) and left ventricular mass index(LVMI) in 19 normal controls and in patients with hypertension, which included 46 obesity and 48 nonobesity. The rate of LVH and relative risk were investigated. Result:The values of LVM were higher in hypertensive patients with obesity than those of hypertensive patients without obesity and normal controls[( 230.18 ± 63.99 )g vs ( 200.48 ± 59.04 )g and ( 161.58 ± 38.54 )g, P< 0.05 , P< 0.01 ]. The values of LVMI were higher in hypertensive patients with obesity than those in normal controls [( 127.81 ± 34.44 )∶ ( 98.01 ± 21.65 ), P< 0.05 ] but were not significantly different between the hypertensive patients with obesity and hypertensive patients without obesity. The rates of LVH in hypertensive patients with obesity were obviously improved compared with those of hypertensive patients without obesity ( 60.9 % vs 39.6 %, P< 0.05 ). The relative risk suffered from LVH in hypertensive patients with obesity was 2.37 times compared with those of hypertensive patients without obesity. Conclusion:Obesity can aggravate left ventricular hypertrophy.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2002年第5期209-210,共2页
Journal of Clinical Cardiology
关键词
高血压
左心室肥厚
肥胖
Hypertension
Left ventricular hypertrophy
Obesity
