摘要
目的 :观察壳聚糖作为牙周引导组织再生膜的生物相容性。方法 :采用冷冻干燥法制备壳聚糖膜 ,然后通过细胞毒性试验、溶血试验、热原试验、过敏试验等体内外生物学试验相结合的方法研究其生物相容性。结果 :测试表明壳聚糖膜无毒、不溶血、不致热、不致敏。结论 :壳聚糖膜具有良好的生物相容性。
Objective: To investigate the biocompatibility of chitosan as membrane for periodontal guided tissue regeneration (GTR). Methods: Chitosan membrane was prepared by freeze drying and tests in vitro and in vivo including cytotoxicity test, haemolysis test, hypersesitive test and pyrogen test, were employed to investigate its biocompatibility. Results: Chitosan membrane showed no toxicity and did not cause hemolysis, pyrogen or hyperergia. Conclusion: Chitosan has desirable biocompatibility.
出处
《山东大学学报（医学版）》
CAS
2002年第2期115-117,共3页
Journal of Shandong University:Health Sciences
基金
山东省自然科学基金资助课题 (Y98CO90 38)
关键词
壳聚糖
生物相容性
引导组织再生
Chitosan
Biocompatibility
guided tissue regeneration
