摘要
目的 :建立注射用银杏叶 (冻干 )有机溶剂甲醇、乙醇、丙酮、乙酸乙酯残留量测定法。方法 :采用顶空GC方法测定注射用银杏叶 (冻干 )有机溶剂残留量 ,使用HP 5固定相的开口毛细管柱 ;以高纯氮为载气 ;以FID为检测器。结果 :该法有良好的线性 ,r在 0 .990 9～ 0 .9999之间 ;精密度、重现性相对标准偏差均小于 5 % ,平均回收率在 93 .0 6 %～1 1 3 .78%之间。结论 :此法简便 ,快速 ,准确 ,可用于中药制剂的甲醇、乙醇、丙酮、乙酸乙酯残留量测定。
Objective:To establish a method for analysis of residual organic solvents (methanol, ethanol, acetone, ethyl acetate) in Ginkgo biloba Leaves for injection.Methods: The contents of residual solvents in Ginkgo biloba Leaves for injection were determined by headspace GC on HP 5 column, with FID detector, high purity nitrogen as the carries gas.Results: There was a good linearity ( r :0.9909～0.9999). The RSD of precision and accuracy was less than 5%, the average recovery rate was in the range of 93.06%～113.78%.Conclusions: The method was simple, quick and accurate and can be used for quality control of Chinese patent medicine.
出处
《中成药》
CAS
CSCD
北大核心
2002年第5期344-346,共3页
Chinese Traditional Patent Medicine
基金
十五国家科技攻关计划项目 (编号:2 0 0 1BA70 1A0 7 2 7)
