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不稳定型心绞痛患者降脂治疗前后血清C-反应蛋白和白细胞介素-6活性变化 被引量:2

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摘要 目的 探讨不稳定型心绞痛患者降脂治疗后血清C -反应蛋白 (CRP)和白细胞介素 6(IL -6)活性的变化。方法 比较 12例不稳定型心绞痛患者用脂必妥治疗前、治疗 4周后血清CRP、IL -6活性水平的变化。结果 ①总胆固醇 (TC)从 (6 5 2± 1 48)mmol/L降至 (5 2 9± 1 0 8)mmol/L ,低密度脂蛋白胆固醇 (LDL -C)从 (4 2 9± 1 2 6)mmol/L降至(2 2 3± 0 87)mmol/L(P <0 0 1)、甘油三酯 (TG)从 (3 62± 0 2 6)mmol/L降至 (2 12± 0 3 7)mmol/L(P <0 0 5 )。②不稳定型心绞痛患者降脂治疗前血清CRP ,IL -6活性明显高于正常人组 (P <0 0 1)。③不稳定型心绞痛患者降脂治疗后CRP从(10 5 6± 1 2 3 )mg/L降至 (8 2 4± 0 87)mg/L ;IL -6从 (11 2± 3 60 )pg/ml降至 (8 2 4± 3 80 )pg/ml ,(P <0 0 1)。不稳定型心绞痛患者治疗前CRP和IL -6无直线相关性 (r =0 18、P >0 0 5 )。结论 降脂治疗可以降低不稳定型心绞痛患者血清炎症因子CRP ,IL
作者 李文晞
出处 《广东医学》 CAS CSCD 2002年第5期495-496,共2页 Guangdong Medical Journal
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参考文献4

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同被引文献16

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