摘要
本研究证实糖尿病患者存在TXA_2/PGI_2比例失衡,表现为血浆TXB_2含量增高,6-keto-PGF_(1α)含量减低。并发微血管病变者,TXA_2/PGI_2失衡更为严重。提示严重的TXA_2/PGI_2比例失衡与糖尿病微血管病变的发生发展有关。
In this study, the existence of ratio imbalance between thromboxane A: (TXA_2) and prostacyclin (PGI_2) in diabetics was confirmed and showing increased plasma level of thromboxane B_2 (TXB_2)and decreased that of 6-keto-prostaglandin F_1α (6-keto-PGF_1α). The ratio imbalance between TXA_2 and PGI_2 become more serious in diabetics with microangiopathy, indicating that serious imbalance between circulating plasma TXA_2 and PGI_2 is concerned with microangiopathy. It is concerned with the occurrance and development of diabetic microangiopathy.
出处
《铁道医学》
1991年第4期206-207,共2页
Railway Medical Journal
关键词
糖尿病
微血管病变
血栓素A2
diabetic nephropathies
diabetic retinopathy
thromboxane A_2
prostaglandins X
