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肝干细胞研究现状 被引量：7

Present status of the study of liver stem cell
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摘要 肝干细胞具有双分化潜能,可向肝细胞和胆管上皮细胞分化发育;胚胎期肝干细胞来源于肝始基,成年期肝干细胞可能来源于Hering管细胞和骨髓造血干细胞;细胞间作用和细胞基质间作用对于肝干细胞的分化成熟起重要作用;肝干细胞在肝脏疾病的基础研究和临床治疗方面具有广阔的应用前景。
作者 万东君 王春雨 李六金
机构地区 中国人民解放军第四军医大学实验动物中心 中国人民解放军第一医院临夏分院
出处 《世界华人消化杂志》 CAS 2002年第4期452-454,共3页 World Chinese Journal of Digestology
关键词 应用 分化 发育 肝干细胞 现状
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献24

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  • 2[2]Dabeva MD, Petkov PM, Sandhu J, Oren R, Laconi E, Hurston E, Shafritz DA.Proliferation and differentiation into adult rat liver. Am J Pathol 2000; 156:2017-2031
  • 3[3]Sigal SH, BrillS, Reid LM, ZvihelI, Gupta S, Hixson D, Faris R, Holst PA.Characterization and enrichment of fetal rat hepatoblasts by immunoadsorption and fluroeseence-activated cell sorting. Hepatology 1994;19:999-1006
  • 4[4]Baumann U, Crosby HA, Ramani P, Kelly DA, Strain AJ. Epression ofthe stem cell faetor reeeptor c-kit in normal and diseaed pediatric liver: identification of a human hepatic progenitor cell. hepatology 1999;30:112-117
  • 5[5]Matsusaka S, Jsujimura T, Toyosaka A, Nakasbo K, Sugihara A, Okamoto E, Vematsu K. Role of c-kit receptor tyrosine kinase in development of oval cells in the rat 2-acetyaminofluorene/partial bepateetomy model. hepatology 1999;29:670-676
  • 6[6]OmoriN, Omori M,Evarts RP, Teramoto T, Miller MJ, Hoang TN,Thorgeirsson. Partial cloning of rat CD34 cDNA and expression during stem cell-dependent liver regeneration in the adult It rat. Hepatology 1997;26:720-727
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同被引文献49

  • 1张刚庆,方驰华,池达智.共同培养诱导骨髓基质干细胞向肝细胞分化的研究[J].中华肝脏病杂志,2005,13(9):648-651. 被引量：13
  • 2Shui-Xiang He,Jin-Yan Luo,Yue-PengWang,Yan-Li Wang,Han Fu,Jun-Li Xu,Gang Zhao,En-Qi Liu.Effects of extract from Ginkgo biloba on carbon tetrachloride-induced liver injury in rats[J].World Journal of Gastroenterology,2006,12(24):3924-3928. 被引量：11
  • 3[2]Petersen BE, Bowen WC, Patrene KD, et al.Bone marrow as a potential source of hepatic oval cells.Science, 1999;284(5) :1168
  • 4[3]Malcolmr A, Richard P, Rosemary J, et al.Hepatocyes from non-hepatic adult stem cells.Nature, 2000;406(7) :257
  • 5[4]Neil D, Theise M, Nimmakayalu, RG ,et al. Liver from bone marrow in humans. Hepatology, 2000 ; 32 (6) : 11
  • 6[5]Lagasse E, Connor H, Al-Dhalimy M, et al. Purified hepatopoietic stemm cell can differentiate into hepatocytes in vivo. Nature Med , 2000 ; 6 (11): 1229
  • 7[6]Avital I, Inderbitzin D, Aoki T, et al. Isolation,characterization and transplantation of bone marrowderived hepatocyte stem cells. Biochem Biophys Res Commun ,2001 ;288(1) :156
  • 8[7]Stewart S. Heterogeneity and plasticity of hepatocyte lineage cells. Hepatology , 2001 ; 33 (3) : 738
  • 9[9]Theise ND, Badve S, Saxena R, et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology, 2000;31(1):235
  • 10Sandhu JS,Petkov PM,Dabeva MD, et al .stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cell[J]. Am J pathol, 2001,159 (4): 1323-1334.

引证文献7

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世界华人消化杂志
2002年 第4期

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