摘要
目的:进一步证实海珠益肝胶囊对肝损伤小鼠的保肝降酶作用。方法:来用卡介苗+脂多糖(BCG+LPS)造成免疫性肝损伤模型小鼠,观察本品对血清中ALT、AST活力单位、肝脾脏器系数和肝脏病理组织学损伤程度的影响。结果:药物能降低血清中ALT、AST活力单位(P<0.01);减小肝脾肿大及脏器系数(P<0.01);减轻肝组织病理损伤程度。结论:海珠益肝胶囊对BCG+LPS所致肝损伤小鼠有明显保肝降酶作用。
Objective: It is evidenced further that Haizhuyigan (HZYG) capsule can protect liver and drop ALT and AST active unite in mice. Method: The model of hepatic damage of immunity by BCG+LPS. Effects of HZYG capsule were observed on ALT and AST active unite in serum, the coefficient of liver and spleen, dimension of hepatic damage in the histopathology. Results:HZYG capsule could drop ALT and AST active unite in serum (P<0. 01) (decrease coefficient of liver and spleen (P<0.01) s reduce dimension of hepatic damage in the histopathology. Conclusion: HZYG capsule can protect the liver from immune damage induced by BCG+LPS in mice.
出处
《中西医结合肝病杂志》
CAS
2002年第2期99-100,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
