摘要
目的 :研究不动杆菌感染和对抗菌药物的耐药性。方法 :对 1996年 1月～ 1999年 12月期间各种感染标本进行不动杆菌培养和药敏试验。结果 :三年中共检出 91株不动杆菌 ,占革兰阴性杆菌 13 4% (91/680 ) ,其中 72株来自呼吸道标本 ,鲍曼不动杆菌是最主要的感染菌种 (74 7% )。 72 9%菌株耐 5～ 16种抗菌药物 ,大多数 β 内酰胺类抗菌药物活性小于 5 0 % ,一代头孢类耐药率明显高于三代 ,而多粘菌素B、氯霉素、庆大霉素 ,卡那霉素 ,链霉素耐药率均大于 5 0 % ;头孢哌酮 /舒巴坦、阿米卡星、妥布霉素、喹喏酮类、哌拉西林、头孢拉定耐药率依次是9 9%、2 3 1%、2 3 4% 2 4 2 %、2 9 7%、2 9 7%。结论 :重视临床感染标本不动杆菌检出及其耐药谱的研究 ,依照药敏试验合理应用抗菌药物 ,以减少细菌耐药产生和传播 。
Objective: To study acinetobacter infection and the spectiun its resistance to antimicrobial agents.Methods: Retrospective study for the acinetobacter culture and drug sensitivity test from all kinds of infections specimen during Jan.1996 Dec.1999.Results: 91 strains of acinetobacter were detected during 3 years.The ratio of the acinetobacter to Gram negative bacilli was 13.4%(91/680).Amony them 72 strains comes from respiratory tract specimen and A.baumanii are most common infectious species(74.7%),72.9%strains are resistant to 5～16 antimicrobial agents.Antimicrobial activity of usual β lactmase antibiotics is <50%,The resistant rate of the first generation cephalosporins in higher than the third generation,all the of PolymyxinB.Chloramyphenicol,Gentamicin,Kanamycin,Streptomycin were >50%,and that of Cefoperazone/Sulbactam,Amikacin,Tobramycin,Fluoroguinolones,Piperacillin,Cefradine were 9.9%,23.1%,23.4%.24.2%.29.7%.29.7% respctively. Conclusion: To strengthen the inspection of the acinetobacter and study for its drug resistance spectrum,according to drug sensitivity test,and rational use of antimicrobial agents,So in order to reduce the ratio of drug resistance bacteria and protect against hospital in fection.
出处
《河南医学研究》
CAS
2002年第1期64-65,共2页
Henan Medical Research
