摘要
基于药物(直接作用于胃肠道的药物除外)起作用必须被吸收进入血液的事实及传统中药口服给药的用药特点,我们建立了从口服中药后血清中直接分离鉴定中药药效物质基础,研究其药代动力学特性的的新方法—中药血清药物化学研究方法。利用该方法已完成了茵陈蒿汤、越桔等中药的系统的血清药物化学研究工作,分析确定了其药效物质基础及药代动力学特性。
On the basis of the fact that the effective components of a drug must be absorbed into the blood and in consideration of the dosing characteristics of traditional oral Chinese drugs a new method for searching effective compounds of drugs directly from serum after taking medicines orally is established and their pharmacokinetic properties are studied. The new method is named Serum Pharmacochemistry Method of Trditional Chinese Medicine, by which, systematic studies on serum pharmacochemistry of such Chinese medicines as Yingchenhaotang,Yue Ju and Yuanzhi have been carried out and their effective components and pharmacodynamic properties analysed and identified.
出处
《世界科学技术-中药现代化》
2002年第2期1-4,共4页
World Science and Technology(Modernization of Traditional Chinese Medicine)
关键词
血清药物化学
中药复方
中药配伍
中医药
serum pharmacochemistry, pharmacokinetics ,compound of Traditional Chinese Medicine
