摘要
目的探讨不同的根治手术方式对胃癌患者术后生活质量的影响。方法对89例行胃癌根治术的患者,根据Spitzer生活质量总体评分量表及Chew-wunWu的特殊症状量表,按不同的胃切除范围(全胃切除、胃次全切除)和淋巴结清扫方式(D2、D3,4)及有无合并脏器切除等分组,在相同时期内进行生活质量的调查及评估。结果89例患者中,术前每组间各项指标差异无显著性意义。在全胃切除(TG)(37例)及胃次全切除(STG)(52例)组中,总体评分及特殊症状评分差异均无显著性意义。D2式淋巴结清扫组(75例)总体评分优于D3,4组(14例)(P<0.05);术后6个月,D3,4组患者腹泻发生率较D2组增多(P<0.05);体重减轻方面,D2组于术后1、3、6个月明显优于D3,4组(P<0.05)。无合并脏器切除组(33例)于术后12个月总体评分、饮食类型、进食量及进餐时间明显优于合并脏器切除组(19例)(P<0.05)。结论全胃或胃次全切除术后的QOL差异无显著性意义;淋巴结清扫范围与术后QOL密切相关,清扫范围越大,术后QOL越差;合并脏器切除对术后QOL有负影响。
Objective To investigate the relationship between the quality of life (QOL) and the different forms of curative resection for the patients with gastric cancer.Methods The items of QOL according to the Spitzer index and Chew wun Wu 14 item index were measured one week preoperatively and 1,3,6,12 months postoperatively among the groups.Results There were neither significant differences in the items of QOL before operation between these groups nor at the different stages after operation between the total and subtotal gastrectomy groups(P >0 05).The patients in D2 lymphadenectomy group had a better QOL especially in Spitzer scoring, diarrhea incidence 6 months postoperatively and weight loss 1,3,6 months postoperatively than those in D3 and D4 lymphadenectomy groups(P< 0 05).The patients without combined dissection had a better QOL 12 months postoperatively than those with combined dissection (P< 0 05). Conclusions There is no significant difference of QOL between the total and subtotal gastrectomy groups.The patients with D2 lymphadenectomy or without combined resection have a better QOL than those with superextended lymphadenectomy(D3,D4) or combined resection.
出处
《中华胃肠外科杂志》
CAS
2002年第1期20-23,共4页
Chinese Journal of Gastrointestinal Surgery
关键词
生活质量
胃切除术
胃癌
治疗
Stomach neoplasms
Quality of life
Gastrectomy
