摘要
ＣＤ４４是细胞粘附分子的重要成员之一，其分布广泛，具有多种生物学功能。近来研究发现 ＣＤ４４参与许多肾脏疾病的发生发展，与炎症细胞的浸润、新月体的形成、系膜细胞的增殖、肾小管间质损伤以及肾移植排斥密切相关。进一步探讨ＣＤ４４在不同肾脏损伤中的作用，对于阐明肾脏疾病的发病及进行性进展的机制和指导治疗具有重要的意义。
出处
《国外医学（儿科学分册）》
2002年第1期12-14,共3页
Foreign Medical Sciences（Section of Pediatrics)
参考文献18
-
1Borland G, Ross JA, Guy K. Forms and functions of CD44[J]. Immunology, 1998,93(2):139 - 148.
-
2Cornelia T, Martin H, Peter H. Splicing choice from ten variant exons establishes CD44 variability[J]. Nucleic Acids Res, 1993,21(5): 1225-1229.
-
3Herrera-Gayol A, Jothy S. Adhesion proteins in the biology of breast cancer: contribution of CD44[J]. Exp Mol Pathol, 1999,66(2): 149-156.
-
4McKee CM, Penno MB, Cowman M, et al. Hyaluronan (HA) frag ments induce chemokine gene expression in alveolar macrophages the role of HA size and CD44[J]. J Clin Invest, 1996,98(10):2403-2413.
-
5Wuthrich RP. The proinflammatory role of hyalurpnan - CD44 interac tions in renal injury[J]. Nephrol Dial Transplant, 1999, 14(11): 2554 - 2556.
-
6Herold-Mende C, Seiter S, Bom AI, et al. Expression of CD44 splice variants in squamous epithelia and squamous cell carcinomas of the head and neck[J]. J Pathol, 1996,179(1):66-73.
-
7Grimme HU, Termeer CC, Bennett KL, et al. Colocalization of basic fibroblast growth factor and CD44 isoforms containing the variably spliced exon v3 (CD44v3) in normal skin and in epidermal skin cancers[J]. Br J Dermatol, 1999,141(5):824-832.
-
8Lewington A J, Padanilam B J, Martin DR, et al. Expression of CD44 in kidney after acute ischemic injury in rats[J]. Am J Physiol, 2000, 278(1):R247 - 254.
-
9Takazoe K, Foti R, Tesch GH, et al. Upregulation of the tumourassociated marker CD44V6 in experimental kidney disease[J]. Clin Exp Immunol, 2000,121(3):523 - 532.
-
10Hara I, Miyake H, Yaamala K, et al. Expression of CD44 adhesion molecules in nonpapillary renal cell carcinoma and normal kidneys[J]. Urology, 1999,54(3):562 - 566.
同被引文献21
-
1陈丹,吴义超.巨噬细胞与肾脏疾病[J].肾脏病与透析肾移植杂志,2004,13(3):256-260. 被引量：12
-
2陈勇,陈志伟,张哲,忻霞菲,何坚,林杭秋.系统性红斑狼疮患者血清可溶性标准型CD44检测及其临床意义[J].中华风湿病学杂志,2005,9(12):738-740. 被引量：2
-
3谢双锋,尹松梅,杨国雷,聂大年,李益清,王秀菊,马丽萍,吴裕丹,王景峰.血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂RGDS对血小板释放反应的影响[J].中山大学学报（医学科学版）,2007,28(2):192-195. 被引量：9
-
4Nakatani K, Fujii H, Hasegawa H, et al. Endothelial adhesion molecules in glomernlar lesions: association with their severity and diversity in lupus models. Kidney Int, 2004, 65: 1290-1300.
-
5Daniel L, Sichez H, Giorgi R, et al. Tubular lesions and tubular cell adhesion molecules for the prognosis of lupus nephritis. Kidney lnt, 2001, 60: 2215-2221.
-
6Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum, 1997, 40: 1725.
-
7Weening JJ, D'Agati VD, Schwartz MM, et al. The classification of glomerulonephritis in systemic lupus erythematousus revisited. Kidney Int, 2004, 65: 521-530.
-
8Daniel L, Saingra Y, Giorgi R, et al. Tubular lesions determine prognosis of IgA nephropathy. Am J Kidney Dis, 2000, 35: 13-20.
-
9Perfumo F, Martini A. Lupus nephritis in children.Lupus, 2005, 14: 83-88.
-
10Varughese GI, Patel JV, Tomson J, et al. Prognostic value of plasma soluble P-selectin and yon Willebrand factor as indices of platelet activation and endothelial damage/dysfunction in highrisk patients with hypertension: a sub-study of the Anglo-Scandinavian Cardiac Outcomes Trial. J Intern Med, 2007, 261: 384- 391.
引证文献2
-
1蒋小云,张巧玲,陈丽植,陆慧瑜,莫樱,陈述枚.狼疮肾炎患儿外周血CD62P和CD44的表达及意义[J].中华风湿病学杂志,2009,13(9):608-611. 被引量：1
-
2刘新,刘立昌,李继平,李朝平,金玉燕,包小丽.壮肾1号颗粒对阿霉素肾病大鼠蛋白尿模型的外周血CD_(44)表达的影响[J].辽宁中医杂志,2012,39(8):1642-1644. 被引量：2
二级引证文献3
-
1王艾琳,刘立昌,刘旭生,刘新.壮肾固精方治疗IgA肾病的网络药理学机制[J].广州中医药大学学报,2022,39(2):410-417. 被引量：3
-
2王利纯,刘立昌,洪炜鸿,金玉燕,曾佳豪,许俊杰.壮肾固精方治疗IgA肾病的临床效果观察[J].中外医学研究,2024,22(32):158-161.
-
3邢莹莹,胡斌,张爱荣.CD62P、CD44对狼疮性肾炎患儿预后不良的预测研究[J].医学检验与临床,2025,36(1):59-64.
-
1何小玲,刘彤,王鹏志,朱理玮,梁晖,邱宇杰,李敏.大鼠小肠移植排斥反应中细胞黏附分子的动态观察[J].天津医药,2001,29(3):168-170.
-
2马利军,邹万忠,张志文,王海燕.肾小球疾病时肾脏组织中细胞间粘附分子－1的表达[J].中华医学杂志,1995,75(4):201-203. 被引量：4
-
3关桂明(综述),杨立川(审校).黏附分子CD146在肾脏疾病中的作用[J].国际泌尿系统杂志,2009,29(1):121-124.
-
4孙雪鹏(综述),汪年松(审校).黏附分子与糖尿病肾病[J].国际泌尿系统杂志,2008,28(2):257-261.
-
5抗肾移植“排斥”新药在我国上市[J].医药世界,2001(5):19-19.
-
6张仕光,陈文岩.肾移植排斥的诊断和治疗[J].中华肾脏病杂志,1989,5(2):84-88.
-
7吕松岑,王新涛,文立臣,韩竹,陶天遵,关德宏.超氧化物歧化酶对骨骼肌I/R后粘附分子表达的影响[J].中华医学杂志,2002,82(12):840-843. 被引量：8
-
8肖建如,曾华武,邵攀东,侯铁胜,贾连顺,赵定麟.血小板活化因子及其受体对颈髓损伤后血脊髓屏障损害的分子机制研究[J].中华骨科杂志,1998,18(3):164-167. 被引量：6
-
9傅耀文,王梦文,计秀生,赵玉千,李胜文.血清可溶性细胞间粘附分子-1在肾移植术后急性排斥监测中的意义[J].中华医学杂志,1998,78(6):452-453.
-
10胡明昌,蔡毅.细胞粘附分子在肾脏疾病中的作用[J].国外医学（儿科学分册）,1996,23(6):285-288. 被引量：1
