脊神经根撕脱后脊髓前角运动神经元死亡的机制
被引量:2
摘要
脊神经根撕脱可引起脊髓前角运动神经元死亡。本文介绍近几年来脊神经根撕脱后脊髓前角运动神经元死亡的病理形态、病理机制及分子机制的研究 ;
出处
《解剖学研究》
CAS
2001年第4期334-336,共3页
Anatomy Research
参考文献10
-
1Chan YM,Wu WT,Yip HK,et al.Caspase inhibitor promote the survival of avulsed spinal motoneurons in neonatal rats[].NeuroReport.2001
-
2Wu WT,Li YF,Frank PS,et al.Expression of c-Jun and neuronal nitric oxide synthase in rat sipnal motoneurons following axonal injury[].Neuroscience Letters.1994
-
3Gillardon F,Klinmaschewshi L,Wickert H,et al.Expression pattern of candidate cell death effector proteins Bax, Bcl-2, Bclxl and c-Jun in sensory and motor neurons following sciatic nerve transection in the rat[].Brain Research.1996
-
4Zhao SR,Pang Y,Roger W,et al.Expression of c-Fos protein in the spinal cord after brachial injury: compasion of root disal nerve transection[].Neurosurgery.1998
-
5Pieper AA,Verma A,Zhang J,et al.Poly ( ADP-ribose )polymerase, nitric oxide and cell death[].TIPS.1999
-
6Nicotera P,Leise M,Manzol L,et al.Neural cell death: a demise with diffferent shapes[].TIPS.1997
-
7Martin LJ,Adeel K,Ann P,et al.Motor neuron degereration after scitic nerve avulsion in adult rat evolves with oxidative stress and apoptosis[].Journal of Neurobiology.1999
-
8Li L X,Lucien J,Houenon,et al.Characterization of spinal Motor neuron degeration following different types of peripheral nerve injury in neonatal and adult mice[].Journal of Computational Neuroscience.1998
-
9Wu WT,Kai H,Li LX,et al.Implantation of PNS graft irhibits the indnction of neuronal nitrie oxide synthase and enhances the surviral of spinal motoneurons following root avalsion[].Experimental Neurology.1994
-
10Li LX,Wu WT,He LF,et al.Rescue of mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor[].Proceedings of the National Academy of Sciences of the United States of America.1995
同被引文献21
-
1袁建军,阚世廉,韩力,王学谦,鲁毅军,宫可同.神经干细胞对脊髓前角运动神经元保护作用的实验研究[J].中华手外科杂志,2004,20(3):171-173. 被引量:5
-
2涂致远,张文明,朱维钦.脊神经损伤后脊髓前角运动神经元保护研究进展[J].福建医药杂志,2005,27(1):124-127. 被引量:2
-
3Reynolds BA,Weiss S.Generation of neurons and astrocytes from isolated cells of the adult mammalian nervous system.Science,1992,255:1707-1710.
-
4Li L,Oppenheim RW,Lei M,et al.Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse.J Neurobiol,1994,25:759-766.
-
5Oorschot DE,McLennan IS.The trophic requirements of mature motoneurons.Brain Res,1998,789:315-321.
-
6Shihabuddin LS,Horner PJ,Ray J,et al.Adult spinal cord stem cells generate after transplantation in the adult dentate gyrus.J Neurosci,2000,20:8725-8735.
-
7Ostenfeld T,Caldwell MF,Prowse KR,et al.Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation.Exp Neurol,2000,164:215-226.
-
8富赛里 马政文 尹岚 等.大鼠脑和脊髓神经干细胞的生物学特性比较[J].中国神经科学杂志,2001,17.
-
9Li L, Oppenheim RW, Lei M, et al.Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J Neurobiol 1994;25(7):759-66.
-
10Oppenheim RW.The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat. J Comp Neurol 1986;246(2):281-6.
引证文献2
-
1张文明,涂致远,朱维钦,林建华,郑志竑,林玲,胡建石.臂丛损伤神经干细胞脊髓前角移植后分化情况及对运动神经元的保护作用[J].中华手外科杂志,2005,21(4):241-244. 被引量:9
-
2涂致远,张文明,朱维钦,郑志,胡建石.脊髓内移植神经干细胞对臂丛神经根性撕脱伤后前角运动神经元生存和修复的影响[J].中国临床康复,2005,9(26):82-85. 被引量:4
二级引证文献10
-
1Na Liu,Feng Li,Longju Chen,Wutian Wu.Expression of nitric oxide synthase in the spinal cord after selective brachial plexus injury[J].Neural Regeneration Research,2006,1(9):773-776.
-
2李晓涛,李长德,解云川,路来金.神经干细胞与雪旺细胞共移植对大鼠臂丛神经根性撕脱伤的疗效[J].中国老年学杂志,2014,34(4):974-975. 被引量:4
-
3张文明,涂致远,朱维钦,林建华.臂丛损伤后神经干细胞脊髓内移植对运动神经元一氧化氮合酶表达的影响[J].实用医学杂志,2007,23(12):1798-1800. 被引量:2
-
4黄灿阳,张文明,朱维钦.神经干细胞移植在脊髓损伤中应用的研究进展[J].福建医药杂志,2007,29(2):100-102. 被引量:1
-
5张辉.干细胞移植修复臂丛神经损伤的应用前景[J].中国组织工程研究与临床康复,2007,11(50):10150-10153. 被引量:1
-
6宣昭鹏,张晓杰,路来金,刘志刚.大鼠臂丛神经根吻合后脊髓病理改变和轴突再生的研究[J].中国修复重建外科杂志,2008,22(9):1077-1081. 被引量:1
-
7李晓涛,路来金.神经干细胞移植用于臂丛神经根性撕脱伤治疗的研究进展[J].中国老年学杂志,2008,28(19):1972-1974. 被引量:1
-
8黄灿阳,张文明,朱维钦.神经根回植术治疗臂丛根性撕脱伤的实验研究[J].福建医药杂志,2011,33(2):71-73. 被引量:2
-
9曹涌,姚羽,朱敏,张烽.人参总皂苷对大鼠脊髓损伤后神经细胞凋亡与再生的影响及相关机制[J].中华手外科杂志,2013,29(6):361-364. 被引量:1
-
10刘志伟,张绍华,丛晓斌,邓静修,陈江海,黄启顺.维甲酸联合Purmorphamine诱导皮肤源性前体细胞向运动神经元分化的研究[J].中华手外科杂志,2018,34(2):131-134. 被引量:1
-
1张文明,朱维钦,林建华.细胞凋亡与周围神经损伤后运动神经元死亡[J].中华创伤杂志,2000,16(1):51-52. 被引量:14
-
2傅永慧,沈涛,吕刚,杨军,付勤,王海义.大鼠脊神经根撕脱后脊髓中Semaphorin3A水平的变化[J].中华创伤杂志,2005,21(9):684-686. 被引量:2
-
3马昭杰.脓毒症急性肾功能衰竭的研究进展[J].医学信息,2013(5):375-376.
-
4戴春富,王正敏,李宽孍.面神经损伤导致其运动神经元死亡的研究[J].临床耳鼻咽喉科杂志,1997,11(6):265-266. 被引量:5
-
5区金锐,侯宝华,王慧玲.重症急性胰腺炎的外科治疗进展[J].岭南现代临床外科,2008,8(5):327-328. 被引量:4
-
6胡永生,李勇杰,陶蔚,张晓华,张宇清,李建宇.中枢性疼痛的神经外科治疗[J].中华神经外科杂志,2011,27(12):1238-1240. 被引量:9
-
7薛丕良,张喜云.浅谈残余肾功能与腹膜透析[J].中国医药指南,2013,11(32):297-298.
-
8王正锋,王瑞华,刘献志,张水军.长期存活的小鼠脊髓缺血损伤模型的建立[J].中华实验外科杂志,2014,31(6):1369-1371. 被引量:2
-
9李蜀光,魏海刚,许彪,邱雅.面神经损伤后面运动神经元死亡的时间进程及电镜观察[J].广东医学,2007,28(8):1240-1242. 被引量:5
-
10王世东.儿童外伤性硬膜外血肿的治疗方式分析[J].中外医疗,2011,30(19):116-116.