摘要
合成防晒剂Cinoxate时,采用方法Ⅰ收率较方法Ⅱ高20%.在制得对甲氧基肉桂酰氯后,省去蒸馏,在原反应器内直接与乙氧基乙醇反应,一步操作制备产品,简化了工艺操作。
In the synthesis of cinoxate, the yield of Method Ⅰ is 20% higher than that of Method Ⅱ. In Method Ⅰ distillation after p-methoxycinnamyl chloride is obtained, is eliminated. P-methoxycinnamyl chloride reacts with ethoxylethanol directly in the original reactor. The final product is obtained in one step only.
