摘要
【目的】探讨伴有慢性蝶窦炎的垂体瘤经蝶窦显微手术方法 ,如何预防继发颅内感染。【方法】对 15例伴有慢性蝶窦炎的垂体瘤患者施行经蝶窦手术 ,术中完整地剥除蝶窦粘膜 ,打开鞍底前及切瘤后 ,用双氧水、酒精及庆大霉素浸泡蝶窦腔及瘤腔各 2次 ,每次 1min ,X线或导航定位下显微放大 8～ 15倍切瘤 ,切瘤后用链霉素粉肌肉浆封闭鞍底 ,术后加强抗炎3～ 5d。【结果】本组肿瘤全切除 12例 ,次全切除 3例 ,无死亡及其他并发症。【结论】慢性蝶窦炎不应再成为经蝶入路的禁忌症。
To study transsphenoidal microsurgery in the treatment of pituitary adenomas with chronic sphenoid sinusitis, and how to prevent secondary intracranial infections. 15 pituitary adenomas with chronic sphenoid sinusitis were removed using the transsphenoidal approach. Sphenoid mucus was completely exenterated before opening of the sellar floor. Hydrogen peroxide, alcohol, and gentamycin solution were instilled into the sinus and the residual cavity after removing the tumor twice, 1 min each time. Tumor was amplified 8 to 15 times and removed under X ray inspection or stereonavigation. Autologous muscle pulp mixed with streptomycin powder was packed into the residual cavity. Intensive antibiotic therapy was continued for 3～5 days postoperatively. 12 tumors were totally removed, 3 were subtotally removed. No one died and no other complications were found. [Conclusion] Chronic sphenoid sinusitis may not be a contraindication for transsphenoidal microsurgery in the treatment of pituitary adenomas.
出处
《中山医科大学学报》
CSCD
北大核心
2001年第6期460-461,共2页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
广东省科委自然基金资助项目 ( 982 780 6 )
关键词
垂体肿瘤
蝶窦炎
并发症
显微外科手术
pituitary neoplasms/surgery
pituitary neoplasms/complications
sphenoid sinusitis/complications
microsurgery/methods
