摘要
经蝶窦入路切除垂体瘤手术已广泛应用。我所自1981年～1987年,采用该手术治疗垂体腺瘤共300例,现报告如下。 临床资料和治疗方法 300例中女性249例、男性51例,年龄10～70岁(平均31.7岁)。已婚241例,未婚59例。
Three hundred cases of various types of pituitary adenoma were treated with trans-sphenoidal microsurgery. There were 249 females and 51 males. 267 of them were secre-tive adenoma, including PRL adenoma 168, GH adenoma 61, GH-PRL mixed adenoma16, GH-TSH mixed adenoma 1,Cushing disease 12, Nelson's syndrome 8 and ACTH-GR-PRL mixed adenoma 1; and 33 cases were non-secretive adenoma. Total tumor re-section was performed in 220 cases(73. 3%)and80 (26. 7%)were partially removed. Aft eroperation 78 cases (51.7%) PRL adenoma resumed normal serum PRL level, 28(18. 5%) decreased more than 50%and 45(29. 8%) less than 50% or no change; 89 cas-es resumed normal menses after operation, 39 of them were pregnant. 30 eases GH ade-noma resumed normal serum GH level, 19 decreased more than 50% and 8 less than50% or no change; acromegaly sign was improved remarkably within a few days afteroperation. 11 cases with GH-PRL mixed adenoma resumed normal serum GH level, 2decreased over 50% and 1 less than 50%; 9 cases resumed normal serum PRL levbl, 2decreased more than 50% and 1 less than 50%; 11 cases resumed normal menses,4 ofthem were pregnant. The 0ushing syndrome sign disappeared in all Cushing's diseasecases, 2 of them were pregnant. 6/8 cases with Nelson's syndrome improved partiallyand 2 showed no response. There was no operative death. The diagnostic method, surgi-cal skill and factors influeneing the curative effect were discussed.
出处
《肿瘤》
CAS
CSCD
北大核心
1989年第2期49-51,共3页
Tumor
