摘要
目的：观察了中药益肾清对大鼠肾毒血清性肾炎的治疗作用。方法：采用 Ｃｌａｒｋｅ方法制备Ｗｉｓｔａｒ大鼠肾毒血清性肾炎模型。结果：益肾清能显著增加实验动物尿量、降低２４ｈ尿蛋白含量及血清尿素氮、血清甘油三酯、血清总胆固醇，升高血清白蛋白，改善肾功能及肾小球的病理改变，减少静脉血栓形成。结论：益肾清对大鼠肾毒血清性肾炎模型具有较好的治疗作用。
Objective: To investigate the therapeutic effects of Yishenqing on nephrotoxic serum glormerulonephritis. Methods: Nephrotoxic serum golormerulonephritis model of rat was created by Clarke methoh. Results: Yishenqing significantly increased urine volume, decreased urine protein, reduced serum urea nitrogen, total cholesterol, and triglyceride, increased serum albumin, improve renal function and patholoical lesions, inhibited formation of venous thrombosis in experimental animals. Conclusion: Yishenqing is effective in treating rat nephrotoxic serum glormerulonephritis.
出处
《中国中西医结合肾病杂志》
2002年第1期10-12,共3页
Chinese Journal of Integrated Traditional and Western Nephrology
关键词
益肾清
肾毒血清性肾炎
实验研究
药理学
Yishenqing Glormerulonephritis Nephrotoxic serum Experimental study
