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Ⅳ.葡萄胎恶性趋势与Ag-NORs的研究

Ⅳ.Ag-NORs IN HYDATIDIFORM MOLE:A MORPHOMETRIC PARAMETER OF MALIGNANT TENDENCY
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摘要 对3组葡萄胎的2种滋养细胞核内的Ag-NORs进行了定量研究。结果表明,葡萄胎、侵蚀性葡萄胎首次刮宫组和侵蚀性葡萄胎组的细胞滋养细胞核内Ag-NORs均数,在各组间的差异均有显著性意义(P<0.01),且依次增高,核内Ag-NORs数目的离散程度也依次增大;合体滋养细胞核内Ag-NORs均数,在各组间差异无显著性意义。结果提示,合体滋养细胞可能是滋养细胞发展过程中的最后成熟阶段;细胞滋养细胞核内Ag-NORs均数及离散程度可做为预测葡萄胎恶性趋势的指标。 Ag-NORs were counted and compared by morphometric method in 30 cases of hydatidiform mole,in 28 cases of first curettage of invasive mole,in 29 cases of invasive mole.The number of Ag-NORs per nuclues of cytotrophoblastic cell was significantly higher in invasive mole and in first curettage of invasive mole than hydatidiform mole(P<0.01),in invasive mole than in the first curettage of invasive mole.The differences were not found in the number of Ag-NORs per nucleus of syntrophoblastic cell among three groups.The dispersity of Ag-NORs increases in sequence with hydatidi- form mole,the first curettage of invasive mole,invasive mole.This result suggests that the number and the dispersity of Ag-NORs may be used as a parameter for distingushing hydatidiform mole from invasive mole.
出处 《山东医科大学学报》 1991年第2期119-122,共4页 Acta Academiae Medicinae Shandong
关键词 AG-NORS 葡萄胎 预后 病理学 Nucleolar orgnizer region-associated argyrophilic proteins Hydatidiform mole Forecasting Pathology
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  • 1D. Ploton,M. Menager,P. Jeannesson,G. Himber,F. Pigeon,J. J. Adnet. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level[J] 1986,The Histochemical Journal(1):5~14

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