摘要
目的 探讨定量门控 (QG) 99Tcm tetrofosmin心肌显像测量左室功能的临床应用价值。方法 74例受试者进行了门控99Tcm tetrofosmin心肌显像 ,采用QGSPECT专用分析程序全自动测量左室功能。其中 36例同时进行静息门控心室显像 ,以比较两种方法测量左室功能的相关性。结果 ①74例99Tcm tetrofosminQGSPECT全自动定量测定左室功能均获成功。②QGSPECT全自动测量 36例受试者的静息左室射血分数 (LVEF)、舒张末期容积 (EDV)、收缩末期容积 (ESV)分别与静息门控心室显像计算结果显著正相关 (r分别为 0 .85 9,0 .914,0 .95 0 ,P均 <0 .0 0 1) ,重复性好。③心肌缺血组 (n =2 8)静息LVEF与对照组 (n =2 3)比较差异无显著性 ,而心肌梗死组 (n =9)静息LVEF明显低于对照组 (t=6 .33,P <0 .0 0 1)。结论 定量门控心肌显像99Tcm
Objective To evaluate clinical value of automatic quantification of left ventricular (LV) function from gated myocardial perfusion SPECT with 99 Tc m tetrofosmin. Methods Gated myocardial perfusion SPECT with 99 Tc m tetrofosmin was performed on 74 cases with different LV function. The LV functional parameters were calculated without operator interaction using a automatic gated myocardial perfusion SPECT processing software (QGSPECT). After gated myocardial SPECT with 99 Tc m tetrofosmin, rest equilibrium radionuclide angiocardiography (ERNA) was performed on 36 cases within 72 h. Results ①Automatic quantification of left ventricular function by gated myocardial perfusion SPECT with 99 Tc m tetrofosmin was successful in 74/74(100%) cases. ② The correlation between rest gated SPECT and ERNA was: r =0.859 for left ventricular ejection fraction (LVEF) ( P< 0.001), 0.914 for end diastolic volume (EDV) ( P <0.001) and 0.950 for end systolic volume (ESV) ( P <0.001). Reproducibility was excellent. ③There was no significant difference (P >0.05) in LVEF at rest between normal subjects (n =23) and ischemic patients ( n =28). LVEF in the patients with myocardial infarct (n =9) was lower than that in normal subjects ( P <0.001). Conclusion The LV function can be accurately evaluated using gated myocardial perfusion SPECT with 99 Tc m tetrofosmin.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2001年第5期278-280,共3页
Chinese Journal of Nuclear Medicine
基金
广东省科技计划项目 (99M0 4 60 4G)
