摘要
血管内皮生长因子 (vascularendothelialgrowthfactor,VEGF)及其受体通过刺激血管内皮细胞分裂增生形成新生血管而促进肿瘤细胞生长、侵袭和转移。如何对其进一步研究来为临床肿瘤诊断与治疗提供一定的帮助已成为近年来肿瘤研究领域的热点之一。
出处
《国外医学(妇幼保健分册)》
2001年第4期171-173,共3页
Foreign Medical Sciences (Section of Maternal and Child Health)
参考文献14
-
1Vincenti V, Cassano C, Rocchi M, et al. Assignment of the vascular endothelial growth factor gene to human chromosome 6p21,3 [J]. Circulation, 1996, 93(1): 1493-1495.
-
2Zhang L, Scott PA, Turly H, et al. Validation of anti-vascular endothelial growth factor antibodies for immunohistochemical localization of VEGF in tissue section: expression of VEGF in the human endothelial[J]. Pathol ,1998, 185(4):102-108.
-
3Lopez-Ocejo O, Vilria-Pelit A, Bequel-Romero M, et al. Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner[J]. Oncogene, 2000 ,19(40):4611-4620.
-
4Laderoute KR, Alarcon RM, Brody MD, et al. Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor [J]. Clin Cancer Res, 2000, 6(7):2941-2950.
-
5Kimitoshi I, Yuichi O, Toshiyaki S, et al. Expression of vascular endothelial growth factor (VEGF) and microvascular density in esophageal squamous cancer[J]. Cancer, 1997, 79(3):206-213.
-
6Suzuki K, Hayashi N, Miyamoto Y, et al. Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma[J]. Cancer Res, 1996,56(13):3004-3009.
-
7Gunningham SP, Currie MJ, Han C, et al. Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: regulation by the von Hippel-Lindau gene and hypoxia[J]. Cancer Res, 2001,61(7):3206-3211.
-
8Cheng WF, Chen CA, Lee CN, et al. Vascular endothelial growth factor and prognosis of cervical carcinoma[J]. Obste Gynecol, 2000,96(Pt1):721-726.
-
9Guidi AJ, Abu-Jawdeh G, Tognazzi K, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endothelial carcinoma[J]. Cancer, 1996,78(3):454-460.
-
10Fine BA, Valente PT, Dey T, et al. VEGF, flt-1, and KDR/flk-1 as prognostic indicators in endothelial carcinoma[J]. Gynecol Oncol, 2000,76(1):33-39.
同被引文献5
-
1[4]Chen CA,Cheng WF,Lee CN,et al.Serum VEGF in epithelial ovarian neoplasms:correlation with patient survival[J].Gynecol oncol,1999,74(2):235-240.
-
2[6]Abulafia O,Sherer DM.Angiogenesis of the ovary[J].Am J Obstet Gynecol,2000,182(1pt1):240-246.
-
3吴莹星,漆秀梅,魏炜.血管内皮生长因子在卵巢上皮性癌中的表达[J].癌症,2000,19(6):565-568. 被引量:12
-
4荆建红,苗薇,董长江.VEGF、P^(53)在卵巢上皮性肿瘤的表达及其与血管生成关系的研究[J].实用妇产科杂志,2001,17(6):346-348. 被引量:4
-
5孙立新,武燕,韩海琼,王全红.检测卵巢上皮性肿瘤患者血清和肿瘤组织中VEGF的临床意义[J].癌症,2003,22(1):58-61. 被引量:13
-
1丁玉梅,马丽丽.Survivin在妇科肿瘤中的研究进展[J].医学综述,2013,19(19):3521-3523. 被引量:3
-
2张鹏,朱晓峰,焦兴元.卵圆细胞的生物学特性及其与原发性肝癌的关系[J].中国普外基础与临床杂志,2015,22(4):494-498. 被引量:4
-
3余畅,邓华瑜.生存素在肿瘤诊断治疗中的研究进展[J].国外医学(临床生物化学与检验学分册),2005,26(11):847-848.
-
4吴素香.生存素及其抗体与恶性肿瘤的诊断和治疗[J].现代预防医学,2009,36(23):4596-4598.
-
5杨永红,李惠芳,朱平.细胞因子诱导的杀伤细胞的研究进展[J].白血病.淋巴瘤,2003,12(2):116-119. 被引量:11
-
6靳波,徐盈斌,刘旭盛.酸性成纤维细胞生长因子生物学特性及其应用研究进展[J].中华损伤与修复杂志(电子版),2010,5(1):55-57. 被引量:19
-
7文庆莲,吴敬波,范娟,郎锦义,唐学清.拓扑替康对人鼻咽癌裸鼠移植瘤放射增敏作用的形态观察[J].中国肿瘤,2004,13(11):735-737. 被引量:1
-
8高书明.癌症是否会遗传?[J].养生大世界,2004(8):37-37.
-
9魏艇,刘文英.肥大细胞与血管瘤[J].中华小儿外科杂志,2006,27(5):265-267. 被引量:1
-
10陈林,范学会.母细胞及母细胞瘤之我见[J].安徽农业技术师范学院学报,1996,10(2):58-59.