摘要
目的:探讨血脂、性激素水平与胆囊结石的关系.方法:选取212例确诊为胆囊结石的患者,测定其血脂TC、TG、LDL-ch、HDL-ch、LDL-ch/HDL-ch及T、E2、P、E2/P,并与72例正常对照组比较.结果:除HDL-ch外,血脂TC、TG、LDL-ch、LDL-ch/HDL-ch各项指标均值,胆囊结石组均高于健康对照组(P＜0.05～0.001).血清T结石组与对照组比较无显著性差异(P＞0.05).E2、P除育龄期结石组外,绝经期及男性结石组均高于对照组(P＜0.05～0.01).育龄期结石组血清P高于对照组(P＜0.01).血清E2虽有升高,但组间比较无显著性差异(P＞0.05).E2/P结石组明显低于对照组(P＜0.01～0.001).结论:脂类代谢及雌性激素代谢紊乱与胆囊结石的发生有明显关系.女性脂类代谢异常更是胆囊结石发生的重要原因之一.
Purpose: To study the relationship between blood lipids, sex hormones and cholelithiasis. Methods: Serum total cholesterol(TC), triglyceride(TG), high density lipoprotein(HDL-ch), low density lipoprotein(LDL-ch) and serum estradiol (E2 ), progesterone ( P), testosterone (T) in 212 patients with cholelithiasis were compared with that of 72 normal persons. Results: Except of HDL-ch, the level of serum TC、 TG、 LDL-ch、 LDL-ch/HDL-ch in patients were higher than those in health persons( P < 0.05 -0.001). Serum T level had not difference between two groups. Except serum P level of the child-bore period women with cholelithiasis, serum E2, P levels in women and men were all higher than that of health persons(P<0.05-0.01). E2/P levels of cholelithiasis were lower than that of health persons(P<0.01 -0. 001) . Conclusion: Blood lipids and female hormones metabolism in cholelithiasis patients with cholelithiasis are disordered.
出处
《临床消化病杂志》
2001年第6期253-254,共2页
Chinese Journal of Clinical Gastroenterology
关键词
血脂
性激素
胆囊结石
Blood lipid Sex hormone Cholelithiasis
