摘要
目的 探讨庚型肝炎病毒 (HGV)感染对慢性丙型肝炎 (CH C)的临床与病理学影响。方法 应用逆转录 聚合酶链反应 (RT PCR)法对 5 3例经肝穿活检确诊的CH C患者血清标本进行了HGV RNA检测 ,并将合并与未合并HGV感染者进行了临床与病理学对比。结果 HGV RNA阳性 1 5例 (2 8 3 0 % )。合并与未合并HGV感染者在临床表现 ,肝功能等生化指标水平 ,HCV RNA阳性率及肝脏病理损害等方面差异均无显著性 (P >0 .0 5 )。结论 HGV感染对CH C的肝脏损害及HCV复制无影响。
Objective To explore the clinical and pathologic effect of hepatitis G virus infection on chronic hepatitis C. Methods HGV-RNA were detected in serum samples from 53 patients diagnosed by liver biopsy with chronic hepatitis C by reverse transcription-polymerase chain reaction. The clinical and pathologic features of the patients with positive HGV-RNA were compared with those of patients with negative HGV-RNA. Results The results showed that 15 patients (28.30%) were positive for serum HGV-RNA and positive rates and the liver pathologic lesions between the two groups(P>0.05). Conclusion These data indicate that HGV coinfection does not affect the liver lesions and HCV replication of chronic hepatitis C.
出处
《临床军医杂志》
CAS
2001年第3期66-69,共4页
Clinical Journal of Medical Officers
