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恶性血液病住院患者医院感染与抗生素应用 被引量:4

Nosocamial Infection and Antibiotic Application of In-patient with Hematological Malignant Disease
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摘要 目的 探讨血液系统肿瘤的医院感染的特点和防治措施。方法 对 5 5 2例血液系统肿瘤住院患者医院感染进行回顾性分析。结果  2 94例发生医院感染率 ,占 5 3 3% ,感染部位以呼吸道感染最多见 ,病原体以G-杆菌为主。结论 血液系统肿瘤患者医院感染与疾病本身和联合化疗导致的免疫抑制和骨髓抑制有关。为减少医院感染 ,应采取有效的预防措施 ,合理使用抗生素。 Objective To study the character and treatment of nosocamial infection of in-patients with hematological malignant tumor. Methods Retrospective analysis of 552 in-patients with hematological malignant tumor. Results The nosocamial infection rate is 53.3%(294/552), the commonest infectious site include throat and respiratory system. Gram-negative bacteria are the commonest causative pathogen and sensitive to piperacillin, the third-generation cephaospirin, and aminoglycosides antibiotic. The sensitive antibiotics to Gram-positive bacteria include cephanospirin, quinolones antibiotic, and vancocin. Conclusion Both of hematological malignant tumors, immunosuppression or/and marrow inhibition result from combined chemotherapy, contribute to the mosocamil infection. Effective prevention and correct antibiotic application should be strengthened to reduce nosocamial infection.
作者 宫超 李莉莉
出处 《临床军医杂志》 CAS 2001年第4期47-49,共3页 Clinical Journal of Medical Officers
关键词 血液系统肿瘤 医院感染 抗生素 hematological malignant tumor nosocamial infection antibiotic
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