摘要
[目的 ]探讨层粘蛋白 ( LN)的表达与肺癌转移及预后的关系。 [方法 ]采用免疫组化 LSAB法检测 96例肺癌 (鳞癌 49例 ,腺癌 47例 )组织中 LN的表达。 [结果 ]LN的表达类型在肺癌不同组织学类型有显著性差异 ( P <0 .0 5 ) ;在不同分化、分级的肺癌中有极显著性差异 ( P <0 .0 0 0 0 1 ) ;在有否淋巴结转移及术后不同生存期的肺癌组织有非常显著性差异 ( P <0 .0 0 1 )。 [结论 ]LN的表达类型可作为判断肺癌细胞分化。
Objective\] To explore the relationship between the laminin (LN) expression and the metastasis?prognosis of lung carcinoma \LN expression of lung carcinoma tissue in 96 cases(the squamosum carcinoma 49 cases, the adenocarcinoma 47 cases) were tested with immunohistochemistry LSAB method \Marked differences in LN expression types were found in different tissue types of lung carcinoma (P<0 05) ; Significant difference were found in different differentiation and different grades of lung carcinoma (P<0 00001) ; Significant difference were found in lung carcinoma tissues in or non lymph nodes metastasis and in different life cycles after operations (P<0 001) \[Conclusion\] LN expression types can be used as an independent judgement parameter for lung carcinoma cell differentiation?lymph nodes metastasis and patients' prognosis \ \
出处
《广西中医学院学报》
2001年第3期8-10,共3页
Journal of Guangxi Traditional Chinese Medical University
关键词
肺肿瘤
层粘蛋白
肿瘤转移
预后
Lung neoplasm
Laminin
Tumor metastasis
Prognosis
