摘要
采用胶银染色技术,对70例喉鳞状细胞癌和25例喉乳头状瘤进行核仁组成区相关嗜银蛋白(AgNORs)的定量研究。结果表明,喉鳞状细胞癌的AgNORs计数高于对照组,喉乳头状瘤的AgNORs计数介于二者之间,差异有高度显著性意义(P<0.01)。在喉鳞状细胞癌中,分化较低者AgNORs计数高于分化较高者,声门上癌AgNORs计数高于声门癌,晚期者AgNORs计数高于早期者,有颈淋巴结转移者AgNORs计数高于无转移者,差异均有高度显著性意义(P<0.01)。提示AgNORs技术是喉肿瘤研究中有价值的手段。
Using silver colloid staining technique, nucleolar-organizer-region-associated argyrophilic proteins (AgNORs) were investigated quantitatively in 70 laryngeal squamous carcinoma and 25 faryngeal papilloma specimens. The results showed that the number of AgNORs varied significantly among the control group, the laryngeal papilloma group and the group with laryngeal squamous carcinoma of different grades. The number of AgNORs was also significantly different between the glotic and supragottic, the early and advanced, the non-metasta-sized and metastasized laryngeal squamous carcinomas (P<0.01). This technique may be valuable in the study
of laryngeal tumors.
出处
《青岛医学院学报》
1991年第4期263-266,共4页
Acta Academiae Medicinae Qingdao Universitatis
关键词
喉肿瘤
核仁组成区
嗜银蛋白
laryngeal neoplasm
nucleolar organizer region
argyrophilic protein
histocytochemistry
