摘要
目的提高临床医师对异位ACTH肿瘤的认识及早期诊断和治疗的可能性。 方法结合文献复习 ,分析 2例异位ACTH肿瘤患者起初的诊断、治疗过程及最终的确诊、治疗过程 ,提出避免误诊、漏诊的措施。 结果 1例患者手术治愈 ,另 1患者术后死于转移性肿瘤所致全身衰竭 ,尸体解剖提示为转移性分秘ACTH肿瘤—类癌。 结论异位ACTH肿瘤临床少见 ,往往表现为柯兴氏综合征 ,诊断困难 ,提高对该病的认识和警惕 ,通过辅助检查 ,综合分析 ,术前能作出正确诊断 。
Objective To enhance the clinicians'recognition of ectopic ACTH secreting tumors and to suggest the possibility of diagnosis and treatment in their early stage. Methods We studied 2 cases of ectopic ACTH tumor in comparison with early and final diagnosis and treatment. Through review of previous reports, we suggested some means to avoid misdiagnosis. Results One patient was cured by surgical intervention, while the other died of general failure caused by metastasis of the ACTH-releasing tumor. Conclusion The ectopic ACTH tumor with its major presentation of Cushing's syndrome, not clinically frequent, is very difficult in diagnosis.But with the enhancement of clinicians'recognition, combined with discrete laboratory examinations and careful analyses, this disease can be well diagnosed before surgical intervention and achieve a satisfactory result.
出处
《上海第二医科大学学报》
CSCD
2001年第4期369-371,共3页
Acta Universitatis Medicinalis Secondae Shanghai
