摘要
[目的 ] 研究血清cTnT测定对急性心肌梗死 (AMI)的诊断价值及其近期心脏事件发生的预测作用。 [方法 ] 137例因胸痛且高度怀疑急性冠状动脉缺血 (AICS)就诊的患者 ,分别于就诊后第 0、8、16、2 4h抽血测血清cTnT和CK- MB ,同时随访心电图检查。 [结果 ] 137例患者中 ,75例诊断为AMI ,以cTnT≥ 0 .2ng/mL诊断AMI的灵敏度为94.7% ,特异度为 91.9% ,以CK- MB≥ 2 3U /L诊断AMI灵敏度为 90 .7% ,特异度为 85 .5 % ;并且随着测得的血清cTnT升高 ,患者住院期间心脏事件发生率亦明显增多。 [结论 ] 急诊胸痛就诊患者 ,早期测定cTnT对诊断AMI价值优于CK- MB ,并且对近期心脏事件发生的机率有预测作用。
To determine the value of serum cardiac tropoini T (cTnT) measurement for diagnosis of acute myocardial infarction (AMI), and the prognostic value of cTnT in patients at emergency department (ED) with acute chest pain. One hundred thirty seven patients with complaint of chest pain suggesting acute ischemic coronary syndrome (AICS) were studied, serum cTnT and CK-MB concentration of these patients were analyzed at 0, 8, 16 and 24 hours after arriving at ED. Among these 137 patients, 75 patients had been diagnosed as AMI based on WHO standard (year 1981). When using a 0.2 ng/mL discrimination level for cTnT, sensitivity for AMI within 24 hours was 94.7% and specificity was 91.9%, for CK-MB≥23U/L, sensitivity was 90.7%, specificity was 85.5%. Elevated cTnT values identify patients at increased risk of cardiac events. [Conclusion] Measurement of cTnT may accurately identify AMI in patients coming to the ED and could predict the prognosis of these patients.
出处
《上海预防医学》
CAS
2001年第10期474-475,共2页
Shanghai Journal of Preventive Medicine
关键词
心肌梗死
肌钙蛋白
预后
诊断
Myocardial infarction
Troponin
Prognosis
