摘要
[目的]提取、分离、筛选高良姜镇痛和止呕作用的有效成分。[方法]用聚酰胺柱、正相硅胶柱、中压液相柱等色谱方法对高良姜有效成分进行了分离、筛选。根据紫外光谱(UV)、红外光谱(IR)、质谱(MS)、核磁共振谱(NMR)分析鉴定化合物的结构。[结果与结论]分得高良姜素和山柰素两者混合晶体和单晶均有镇痛和止呕的药理作用,并确定高良姜素为药材质控标准的对照品。
ive] To isolate the active constituents with analgesic and antemetic actions from Rhizo-ma Alpiniae Officinarum. [Methods] Polyamide and silica gel column chromatography was used to isolate and extract the analgesic and antemetic constituents. The structure of compounds was identified by ultra violet spectroscopy, infrared spectroscopy, mass spectroscopy and nuclear magnetic resonance spectrosco-py. [ Results ] Galangin and kaempferide are identified as the analgesic and antemetic constituents. [Conclusion] Galangin can be used as the quality control for Rhizoma Alpiniae Officinarum.
出处
《广州中医药大学学报》
CAS
2001年第3期240-242,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
国家"九五"攻关课题(编号:96-903-02-04)
关键词
高良姜
高良姜素
分离
提纯
山奈素
镇痛
止呕
有效成分
ALPINIA OFFICINARUM/standards
GALANGIN/isolation & purification
GALANGIN/chemistry
KAEMPFERIDE/isolation & purification
KAEMPFERIDE/chemistry
