摘要
①目的 探讨肿瘤坏死因子α(TNF α)和可溶性白细胞介素 2受体 (sIL 2R)与急性白血病的关系。②方法 用双抗夹心ELISA方法 ,检测 78例急性白血病病人发病期和缓解期血清TNF α和sIL 2R水平 ,并与 43例健康献血员进行比较。③结果 ANLL和ALL病人血清TNF α和sIL 2R水平均较正常对照组显著升高 (F =4.93,5 .2 5 ,q =3 .0 2～ 4.34,P <0 .0 1) ,急性白血病病人缓解前和缓解后的TNF α和sIL 2R测定结果有明显差异(F =3 .98,4.5 2 ,q =5 .16～ 6 .0 7,P <0 .0 1)。 ④结论 监测急性白血病病人血清TNF α和sIL
Objective To explore the relation between TNF-α,sIL-2R and acute leukemia. \ Methods The TNF-α and sIL-2R were assayed with ELISA in 78 cases of acute leukemia. \ Results The serum levels of TNF-α and sIL-2R in patients with acute leukemia were higher than those of normal controls(F= 4.93, 5.25 , q=3.02-4.34,P<0.01), and there was a significant difference between before and after remission(CR) (F=3.98,4.52,q=5.16-6.07,P<0.01). \ Conclusion The determination of serum TNF-α and sIL-2R levels was valuable in the diagnosis and evaluation of therapeutic effect for acute leukemia.
出处
《齐鲁医学杂志》
2001年第2期85-86,共2页
Medical Journal of Qilu
