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大鼠离体作功心脏心钠素释放的动态观察

OBSERVATION OF ATRIAL NATRIURETIC PEPTIDE RELEASE FROM RAT ISOLATED WORKING HEART
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摘要 采用心钠素放射免疫测定和免疫组化法对离体大鼠心脏心钠素的释放进行了动态观察。研究发现,大鼠离体作功心脏心钠素的释放在一定时限内基本保持在同一水平。提示大鼠离体作功心脏灌流模型用于研究某些因子对心钠素释放的影响是可行的。 The duration of atrial natriuretie peptide (ANP) release from atria was observed by specific radioimmunoassay and immunocytochemical analysis on isolated perfussed working heart of the rats, We found that the release of ANP from atria is consistently maintained within a limited time, The rat working heart perfusion modcl is indeed a feasible approach in determing the factrs that affect reiease of ANP in vitro.
出处 《南京铁道医学院学报》 1991年第1期31-34,共4页 Journal of Nanjing Railway Medical College
关键词 心脏 心纳素 放射免疫测定 大鼠 rats heart natriuretic peptides, atrial radioimmunoassay immunoenzyme technies
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参考文献1

  • 1Heikki Ruskoaho,Hinrich Th?lken,Rudolf E. Lang. Increase in atrial pressure releases atrial natriuretic peptide from isolated perfused rat hearts[J] 1986,Pflügers Archiv European Journal of Physiology(2):170~174

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