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依西美坦的合成 被引量:6

Synthesis of Exemestane
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出处 《中国医药工业杂志》 CAS CSCD 北大核心 2001年第8期345-346,共2页 Chinese Journal of Pharmaceuticals
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参考文献5

  • 1[1]Pranco B, Emico DS, Antonio L, et al. Synthesis and aromatase inhibition by potential metabolites of exemestane(6-methylenandrosta-1,4-diene-3,17-dione)[J]. Steroids, 1993, 58(11)∶527-532.
  • 2[2]Antonio L, Paolo L. Process for the preparation of methylene derivatives of androsta-1,4-diene-3,17-dione as aromatase inhibitors[P]. EP: 307 134, 1989-03-15. (CA 1989, 111∶134643f)
  • 3[3]Antonio L, Paolo L. Synthesis of 6-methylene derivatives of androsta-1,4-diene-3,17-dione, useful as aromatase inhibitors, via Mannich reaction and dehydrogenation[P]. EP: 326 340, 1989-08-02. (CA 1989, 112∶36257j)
  • 4[4]Franco B, Emico DS, Paolo L, et al. Preparation of substituted androsta-1,4-diene-3, 17-dione and their use for treating hormone-relating cancers[P]. DE: 3622841, 1987-02-15. (CA 1987, 106∶162586e)
  • 5[5]Turner AB, Ringold HJ. Applications of high-potential quinones. Part 1. The mechanism of dehydrogenation of steroidal ketones by 2, 3-dichloro-5, 6-dicyanobenzoquinone[J]. J Chem Soc (C), 1967, 1720-1730.生物技术

同被引文献28

  • 1杨曼瑾 郭传勇.抗肿瘤药-依西美坦[J].国外医药合成药生化药制剂分册,2000,21(5):300-300.
  • 2FERNANDES P,CRUZ A,ANGELOVA B.Microbial conversion of steroid compounds:recent developments[J].Enzyme and Microbial Technology,2003,32 (6):688-705.
  • 3ZHANG L T,WANG M,SHEN Y B.Improvement of Steroid Biotransformation with Hydroxypropyl-β-Cyclodextrin Induced Complexation[J].Appl Biochem Biotechnol,2009,159 (3):642-654.
  • 4GARY J S,DOUGLAS B K.Solvent selection for whole cell biotransformations in organic media[J].Critical Reviews in Biotechnology,1995,15(2):139-177.
  • 5JIRADEJ M,PATTANA S,ARANYA M.Biotransformation of chlormadinone acetate to dehnadinone acetate by free and immobilized Arthrobacter simplex ATCC6946 and Bacillus sphaericus ATCC 13806[J].Enzyme and Microbial Technology,2000,33(2):320-325.
  • 6CRUZ A,FERNANDES P,CABRAL J M S,et al.Whole-cell bioconversion of β-sitosterol in aqueous-organic two-phase systems[J].Journal of Molecular Catalysis B:Enzymatic,2001,11(4):579-585.
  • 7LONGO.Synthesis of 6-methylene derivatives of androsta-1,4-diene-3,17-dione:美国,4990635[P].1991-05-26.
  • 8熊宗贵.发酵工艺原理[M].北京:中国医药科技出版社,2000..
  • 9张春燕,白宝星,王明蓉.甾体药物生物转化体系的研究进展[J].国外医药(抗生素分册),2007,28(5):210-214. 被引量:7
  • 10李惠平,季加孚,侯宽永,贾廷珍,赵红梅,肖宇,王墨培,汪有蕃.芳香化酶抑制剂治疗晚期乳腺癌的临床研究[J].北京大学学报(医学版),2007,39(2):193-196. 被引量:8

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