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血管生成素与肿瘤新生血管生成 被引量:5

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摘要 血管生成素Angiopoietin是特异性作用于血管内皮细胞的生长因子 ,主要由Angiopoietin 1和Angiopoietin 2组成。Tie 2是其共同受体。Angiopoietin 1能保持血管内膜的稳定性 ,与VEGF协同作用 ,促使血管成熟。Angiopoietin 2能拮抗Angiopoietin 1的作用 ,破坏血管的稳态。在肿瘤血管生成过程中 ,Angiopoietin 2表达于肿瘤侵袭的最前沿 ,是血管产生的早期信号。阻断Angiopoietin/Tie
作者 方全
出处 《国外医学(生理病理科学与临床分册)》 2001年第5期345-347,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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同被引文献65

  • 1李小静,孟刚.瘢痕微血管构筑与瘢痕形成及康复治疗相关性的研究进展[J].中国组织工程研究与临床康复,2001,10(18). 被引量:6
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  • 3乔丽娟,田艳伟.苏木抗癌有效成份作用荷瘤小鼠TSGF的观察[J].山西职工医学院学报,2001,11(2):5-6. 被引量:15
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