摘要
1986年9月～1987年6月,新疆和田发生了一次非甲非乙型肝炎(HNANB)的流行,以病原学排除法判明,为肠道传播的非甲非乙型肝炎病毒所致。为了制订本病的隔离期限和控制对策提供科学依据,并为了研究其流行病学、临床学和病原学特点,我们用免疫电镜检测了6名自然感染的HNANB病人在潜伏期和急性期的60份系列粪便标本,以了解其排毒规律。现将结果报告如下。
A total of 60 stool samples collected from 6 patients suffering from acute enterically transmitted non-A, non-B hepatitis were examined by immune electron microscopy ( IEM ) during an epidemic of the disease in Hetian area,Xinjiang in 1986-1987. The virus was found in feces in 5 patients, and 28.3 per cent ( 17/60 ) of the samples collected. All 3 stool samples collected 1-4 days before illness were positive for the virus. The rate of virus excretion gradually declined from 1-9 days after the onset. 14.3 per cent ( 1/7 ) of the stool samples excreted virus within 10-12 days after the onset, whereas virus was not detected in 22 samples collected 13-24 days after the onset.In 94.1 per cent of samples, the virus were obtained during late incubation period and early acute phases when SGPT was under 100IU/L. In view of thesd findings we suggest that the isolation period for this disease should be at least 2-3 weeks from the onset of the disease.
出处
《病毒学报》
CAS
CSCD
北大核心
1989年第2期188-190,共3页
Chinese Journal of Virology
关键词
丙型肝炎
病毒
排泄
肠道
传播
Non-A, non-B hepatitis Virus-like particles Immune electron microscopy Isolation period
