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非小细胞型肺癌中凋亡相关基因的表达与胎盘型谷胱甘肽硫转移酶的关系 被引量:1

Relation of between the expression of apoptosis-associated genes and gat-pi in non-small-cell lung cancer
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摘要 利用临床诊断为非小细胞型肺癌的手术标本 ,通过改良的免疫电镜胶体金标记、图象分析和免疫组化方法 ,检测 GST- Pi的超微结构定位以及 BCL- 2和 BAX在肺癌中的表达。结果显示 GST- Pi与 bcl- 2的表达呈负相关性 ,而 GST- Pi与 The immunohistochemistry ,histomophometrlg and colloidal gold lableld immunoelectron microscope techniques were used to examine the expression of apoptosis associated genes-bcl 2,bax and ultrastructural location of glutathion s transferase pi.in 23 specimens of non small cell lung cancer. Conclusion:The expression of bcl 2 and glutathion s transferase pi in non small cell lung cancer indicated negative corelation.but there was no relation between the expression of bax and glutathion s transferase pi.
出处 《山东医药》 CAS 北大核心 2001年第16期14-15,共2页 Shandong Medical Journal
基金 山东省卫生厅基金资助 94鲁卫科字 2 0
关键词 凋亡基因 胎盘型谷胱甘肽硫转移酶 超微结构 非小细胞肺癌 lung lung cancer ultrastructure bcl 2 bax glutathion-s-transferasepi
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