摘要
转化生长因子 β1作为一种细胞生长和肿瘤恶化的潜在抑制剂 ,失去这一负向调节能刺激肿瘤发展。文章重点介绍了转化生长因子 β1在结肠癌患者中作为肿瘤标记物的潜能 ,其表达水平与该病复发率、患者生存率的关系 ,并简述了转化生长因子 β1在肝硬化。
Transforming growth factor β 1(TGF β 1) acts as a potent inhibitor of cell growth and tumor progression but loss of this negative regulation can contribute to tumor development This article describes the latnet possibility that TGF β 1 acts as tumor marker in patients with colorectal carcinoma,and the relationship among the TGF β 1 level with recurrence and survial Furthermore,it gives the application of TGF β 1 in cirrhotic hepatocellular carcinoma and bladder carcinomas
出处
《药物生物技术》
CAS
CSCD
2001年第4期227-229,共3页
Pharmaceutical Biotechnology
关键词
转化生长因子Β1
肿瘤标记
结肠癌
肝硬化
膀胱癌
抑制剂
Transforming growth factor-β 1,Tumor marker, Colorectal carcinoma,Cirrhotic hepatocellular,Bladder carcinomas
