摘要
目的 :观察米索前列醇直肠用药对剖宫产产后出血的预防效果。方法 :选择 3 5 0例剖宫产患者 ,随机分为两组。治疗组 176例 ,麻醉成功后立即用米索前列醇 6 0 0 μg塞入直肠内 ;对照组 174例 ,胎儿娩出后立即宫体肌肉注射缩宫素 2 0U。测量并记录术中及术后 2 4h内出血量。结果 :术中及术后 2h内出血量、术后 2～ 2 4h出血量和产后出血的发生率 ,治疗组分别为 (2 89.3± 83 .3 ) ,(5 4.1± 14 .2 )mL和 9.7% ,对照组分别为 (3 3 8.4± 88.5 ) ,(75 .1± 2 2 .8)mL和2 5 .9%。两组比较差异均有显著性统计学意义 (P <0 .0 5 )。结论 :米索前列醇直肠用药能较好地预防剖宫产产后出血 ,且用药经济、方便。
Objective:To observe the preventing effect of misoprostol on hemorrhage after cesarean section. Methods:Three hundred and fifty patients receiving cesarean sections were randomized into two groups:misoprostol group (n=176), 600 μg misoprostol was given rectally when anesthesia was successfully performed; oxytocin group (n=174), 20 U oxytocin was injected into uterine muscle immediately after delivery of baby. The bleeding amount within 24 hours after delivery was measured. Results:The bleeding amount within 2 hours and from 2 to 24 hours after delivery in misoprostol group were lower than those in oxytocin group [respectively, (289.3±83.3) mL vs. (338.4±88.5) mL, and (54.1±14.2) mL vs. (75.1±22.8) ml, P<0.05]. The incidence of hemorrage in misoprostol group was also lower than that in oxytocin group (9.7% vs. 25.9%, P<0.05). Conclusion:Misoprostol is more effective than that of oxytocin in reduction of cesarean section.
出处
《医药导报》
CAS
2001年第7期418-419,共2页
Herald of Medicine
