摘要
目的 探讨米索前列醇联合缩宫素预防剖宫产术后出血的的临床效果。方法 选择90例剖宫产病人随机分为A、B、C三 组,均为30 例, A 组当腹膜切开后由巡回护士戴无菌手套一次性直肠置米索前列醇600μg(距肛门约3 cm) ,B 组在胎儿娩出后,立即在宫体注射缩宫素20 U 。C 组当腹膜切开后由巡回护士戴无菌手套一次性直肠置米索前列醇600μg,同时于胎儿娩出后在宫体注射缩宫素20 U。结果 从用药到宫缩出现的时间, 以4 分钟时限结果对比, C组25例(83.3%) , B 组11 例(36.7%), A组20例(66.7%), C组与其它两组有显著差异( P < 0. 05);C 组出血量为150.8±80.4ml,较A 、B 两组(分别为246.00±98.9,398.8±120.5)要少,差异有极显著性统计学意义( P < 0. 01)。结论 米索前列醇与缩宫素联合使用可明显加强子宫收缩, 减少剖宫产术后出血量。
Objective To observe the clinical effectiveness of combination therapy with misoprofiland oxytocin on preventing postpartum hemorrhage in cesarean section Methods Ninety women withcesarean section were assigned randomly to group A 、B and C. Group A (30 patients) took intra-rectummisoprostal tablet 600μg after theperitoneum was opened,B (30patients) routinely used oxytocin at thedose 20U locally while the fetal was delivering with operation.,and C (30 patients) combinedmisoprostal with oxytocin .Results In group C ,25 (83.3%)cases had uterine contraction within 4minut after treatment, and was significently difference from other two groups( P< 0. 05).The averagehemorrhage in groupC was 150.8±80.4ml,and was significantly lower than in groupA and B(246.00±98.9,398.8±120.5 respectively). Conclusion To combine misoprofil and oxytocin on preventingpostpartum hemorrhage in cesarean section showed the effect rapidly and resulted strong uteruscontraction. prevention and treatment of hemorrhage in cesarean section was definite.
出处
《国际医药卫生导报》
2004年第12期23-24,共2页
International Medicine and Health Guidance News
关键词
米索前列醇
缩宫素
联合用药
剖宫产术
产后出血
Misoprostol Oxytocin Cesarean section Postpartum hemorrhage Combination Therapy
