摘要
目的 :探讨神经心理学量表、脑电生理及 MRI检查在脑梗死患者临床评估中的价值。方法 :对 5 5例脑梗死患者发病后一个月进行神经心理学上脑高级功能的评估 ,并进行了常规脑电图 ,P30 0及 MRI检查。其中神经心理学量表的检查包括 MMSE、韦氏智力及临床记忆量表检查。结果 :智商、临床记忆量表得分及 P30 0潜伏期检查患者组较对照组下降有明显差异。MRI所显示的病变大小与患者的认知功能和短时记忆明显相关。P30 0潜伏期不仅与认知功能明显相关 ,而且与韦氏智力有一定的相关性。结论 :合理的应用神经心理学量表检查可以全面地反映不同脑梗死患者脑功能障碍的不同侧面。脑梗死面积大小明显影响患者的认知功能和短时记忆。P30 0可以作为脑梗死患者认知功能评估的敏感指标。
Objective:To determine the value of psychometric, electrophysiological and MRI study in detection and evaluation ofimpairment in patients with ischemic stoke. Methods: Cognitive, intelligence and memory function were assessed in 55 ischemic patients subjected to psychometric, electrophysiological and MRI evaluation. The psychometric tests included: MMSE, WAIS RC and clinical memory scales. electrophysiological evaluation used conventional electroencephalography and P300. Results: Patients did significantly worse than normal controls in WAIS RC scale clinical, memory scale and P300 latency. The size of infarction was related to impairment of cognitive function. P300 latency correlated negatively with impairment of cognitive function and intelligence performance in stroke patients. Conclusion: It is necessary to using psychometric scales properly in determining the patterns of cognitive impairment. We concluded that impairment of cognitive and recent memory in ischemic patients is related to the size of infarction. Out of the clinical electrophysiological tests, P300 latency is most significantly affected parameter in detecting the cognitive impaiment.
出处
《脑与神经疾病杂志》
2001年第4期210-213,共4页
Journal of Brain and Nervous Diseases
关键词
脑梗死
认知功能
P300
脑电图
MRI
Cerebral infarction Cognitive function Electroencephalography P300 MRI
