摘要
目的 :探讨颈动脉粥样硬化对脑梗死患者认知功能及近期预后的影响。方法 :对 112例脑梗死患者的颈动脉进行彩色多普勒超声检查 ,并对患者进行了简化智能状态量表 (MMSE)、记忆力、计算力、注意力、反应速度、视空间等多项神经心理测验 ,同时对患者入院时、第 3～ 4周的神经功能缺损进行评分 (SSS)。结果 :脑梗死患者多项神经心理检测记分较健康对照组低 ,有颈动脉粥样硬化的脑梗死患者较无颈动脉粥样硬化的脑梗死患者记分低 ,以严重颈动脉粥样硬化及严重颈动脉狭窄的脑梗死患者降低最为明显 ;颈动脉粥样硬化程度与认知功能障碍程度呈正相关。有颈动脉粥样硬化的脑梗死患者入院时SSS计分高于无颈动脉粥样硬化的脑梗死患者 ,近期预后差。结论 :颈动脉粥样硬化可影响脑梗死患者的认知功能 ,有颈动脉硬化的脑梗死患者缺血性损伤严重 ,影响脑梗死患者的近期预后。
Objective: To investigate the effects of carotid arteriosclerosis on cognitive functions and current prognosis in patients with cerebral infarction. Methods: Extracranial carotid arteries were assessed using dopple ultrasongraphy in 112 patients with cerebral infarction. Cognitive functions were evaluated with the Mini-Mental state Examination (MMSE) and five neuropsychological tests assessing memory, attention, calculation psychomotor rapidity and visuospatial perception. Deficits in neurological functions were assessed on admission and 3 to 4 weeks. Results:All neuropsychological measures were found to be poorer in patients with carotid arteriosclerosis than those with no carotid arteriosclerosis, especially in cases with severe carotid arteriosclerosis and severe carotid stenosis. There was a positive relationship between severity of carotid arteriosclerosis and change in cognitive functions. The scores of SSS were higher on admission in cerebral infarction patients with carotid arteriosclerosis. Recent prognosis was also poorer in patients with carotid arteriosclerosis.Conclusions: Significant effect of carotid arteriosclerosis was shown on cognitive functions of patients with cerebral infarction. As cerebral ischemic injury is severe, prognosis in cerebral infarction patients with carotid arteriosclerosis is poor.
出处
《中国临床心理学杂志》
CSCD
2002年第1期20-22,共3页
Chinese Journal of Clinical Psychology
关键词
动脉粥样硬化
脑梗死
认知
预后
Arteriosclerosis
Carotid
Cerebral infarction
Cognition
