摘要
目的 :应用交感神经皮肤反应检查法 (SSR)定量评价脑梗死患者的交感神经反射活动 ,并探讨其植物神经中枢调节机制。方法 :对 42例急性期脑梗死患者 ,利用肌电图仪刺激双侧正中神经记录SSR ,并以 30例健康人作对照组进行研究。结果 :脑梗死急性期病灶同侧SSR异常 38例 (90 % ) ,对侧为 30例 (71% )。皮层梗死组主要表现为双侧SSR波幅对称性降低 ,与对照组比较差异非常显著 (P <0 0 0 1)。内囊—基底节区梗死组的异常表现形式有SSR缺失 ,双侧波幅降低 (同侧 :P <0 0 0 1,对侧 :P <0 0 1) ,以病灶同侧波幅降低更显著。结论 :SSR可定量评价脑梗死患者的交感神经功能状态 ,对脑梗死患者的植物神经功能障碍有亚临床诊断价值 ;脑梗死急性期可致SSR抑制 ,内囊—基底节区对植物神经系统有重要的调节作用。
Objective:To asses quantitatively the sympathetic reflex activity in patients with cerebral infarction,and explore the regulation mechanism of autonomic nerve center.Methods:Sympathetic skin response(SSR) was determined in 42 patient with cerebral infarction by NDI-400 EMG instrument,and 30 normal subjects were served as controls.Results:Ipsilateral abnormality of SSR was found in 38 ones of the 42 patients (90%),and the contralateral abnormality in 30 ones (71%) in the acute stage of cerebral infarction.In patients with cortical infarction,the abnormality of SSR mainly showed bilateral symmetric decreace of the amplitude.A significant differance was noted as compared with the control group ( P <0 001).In patients with internal capsular-basal ganglia infarction,the abnormality of SSR mainly included the disappearance of SSR and bilateral decrease of the SSR amplitude,esp the ipslateral of the focus.Conclusion:SSR might be used as an objective index to asses quantitatively the condition of sympathetic nerve function in patients with cerbral infarction,and might be of diagnostic value in the subclinical autonomic nerve dysfunction.SSR might be suppressed in the acute stage of cerebral infarction,and the internal capsular-basal ganglia might have important effects on regulating the autonomic nervous system.
出处
《临床神经电生理学杂志》
2001年第3期139-143,共5页
Journal of Clinical Electroneurophysiology
关键词
交感神经皮肤反应
脑梗死
诊断
Sympathetic skin response
Cerebral infarction
